Thomas L Rothstein, MD, PhD
- Chair, Department of Investigative Medicine
- Professor, Department of Investigative Medicine
-
- Primary Address
- Office
- Western Michigan University Homer Stryker M.D. School of Medicine
- 1000 Oakland Drive
- Kalamazoo, MI, United States 49008
Publications
Publications
- Husain-Krautter S., Lee J., Vos D., Gallego J.A., Malhotra A.K., Rothstein T.L., Skewing of the antibody repertoire in cerebrospinal fluid B cells from healthy controls and patients with schizophrenia, Behavioural Brain Research, 2022-03-26 00:00:00. (Journal).
Published, 03/26/2022.
https://www.scopus.com/inward/record.uri?partnerID... - Kaku H., Ludlow A.V., Gutknecht M.F., Rothstein T.L., Fas Apoptosis Inhibitory Molecule Blocks and Dissolves Pathological Amyloid-β Species, Frontiers in Molecular Neuroscience, 2021-12-14 00:00:00. (Journal).
Published, 12/14/2021.
https://www.scopus.com/inward/record.uri?partnerID... - Khan N., Hu Y., Lowell C.A., Rothstein T.L., Signal integration by translocation and phosphorylation of PKCd in the B Cell alternate pathway, Journal of Immunology, 2021-11-01 00:00:00. (Journal).
Published, 11/01/2021.
https://www.scopus.com/inward/record.uri?partnerID... - Yu L., Lemay P., Ludlow A., Guyot M.C., Jones M., Mohamed F.F., Saroya G.A., Panaretos C., Schneider E., Wang Y., Myers G., Khoriaty R., Li Q., Franceschi R., Engel J.D., Kaartinen V., Rothstein T.L., Justice M.J., Kibar Z., Singh S.A., A new murine Rpl5 (uL18) mutation provides a unique model of variably penetrant Diamond-Blackfan anemia, Blood Advances, 2021-10-26 00:00:00. (Journal).
Published, 10/26/2021.
https://www.scopus.com/inward/record.uri?partnerID... - Ludlow A., George N., Glassford M., Udenberg K., Hannibal M.C., Schwalm C., Scott K., Rothstein T.L., Singh S.A., The Use of B-Cell Polysome Profiling to Validate Novel RPL5 (uL18) and RPL26 (uL24) Variants in Diamond-Blackfan Anemia, Journal of Pediatric Hematology/Oncology, 2021-04-01 00:00:00. (Journal).
Published, 04/2021.
https://www.scopus.com/inward/record.uri?partnerID... - Khan N., Rothstein T.L., The Alternate Pathway for BCR Signaling Induced by IL-4 Requires Lyn Tyrosine Kinase, Journal of Molecular Biology, 2021-01-08 00:00:00. (Journal).
Published, 01/08/2021.
https://www.scopus.com/inward/record.uri?partnerID... - Tsuji N., Rothstein T.L., Holodick N.E., Antigen Receptor Specificity and Cell Location Influence the Diversification and Selection of the B-1a Cell Pool with Age, Journal of immunology (Baltimore, Md. : 1950), 2020-08-01 00:00:00. (Journal).
Published, 08/01/2020.
https://www.scopus.com/inward/record.uri?partnerID... - Kaku H., Rothstein T.L., FAIM Is a Non-redundant Defender of Cellular Viability in the Face of Heat and Oxidative Stress and Interferes With Accumulation of Stress-Induced Protein Aggregates, Frontiers in Molecular Biosciences, 2020-02-27 00:00:00. (Journal).
Published, 02/27/2020.
https://www.scopus.com/inward/record.uri?partnerID... - Kaku H., Ludlow A.V., Gutknecht M.F., Rothstein T.L., FAIM Opposes Aggregation of Mutant SOD1 That Typifies Some Forms of Familial Amyotrophic Lateral Sclerosis, Frontiers in Neuroscience, 2020-02-21 00:00:00. (Journal).
Published, 02/21/2020.
https://www.scopus.com/inward/record.uri?partnerID... - Guo B., Ludlow A.V., Brightwell A.S., Rothstein T.L., Impairment of PD-L2 positive B1a cells enhances susceptibility to sepsis in RasGRP1-deficient mice, Cellular Immunology, 2019-12-01 00:00:00. (Journal).
Published, 12/2019.
https://www.scopus.com/inward/record.uri?partnerID... - Upadhye A., Srikakulapu P., Gonen A., Hendrikx S., Perry H.M., Nguyen A., McSkimming C., Marshall M.A., Garmey J.C., Taylor A.M., Bender T.P., Tsimikas S., Holodick N.E., Rothstein T.L., Witztum J.L., McNamara C.A., Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked to Human Coronary Atherosclerosis, Circulation research, 2019-10-25 00:00:00. (Journal).
Published, 10/25/2019.
https://www.scopus.com/inward/record.uri?partnerID... - Ghosn E., Dorshkind K., Herzenberg L.A., Holodick N., Kantor A., Montecino-Rodriguez E., Rothstein T.L., Silverman G., Yang Y., Yoder M.C., Yoshimoto M., B1 B cell progenitors, Science, 2019-04-19 00:00:00. (Journal).
Published, 04/19/2019.
https://www.scopus.com/inward/record.uri?partnerID... - Rodriguez-Zhurbenko N., Quach T.D., Hopkins T.J., Rothstein T.L., Hernandez A.M., Human B-1 cells and B-1 cell antibodies change with advancing age, Frontiers in Immunology, 2019-01-01 00:00:00. (Journal).
Published, 2019.
https://www.scopus.com/inward/record.uri?partnerID... - Gallego J., Blanco E., Husain-Krautter S., Madeline Fagen E., Moreno-Merino P., del Ojo-Jiménez J., Ahmed A., Rothstein T., Lencz T., Malhotra A., Cytokines in cerebrospinal fluid of patients with schizophrenia spectrum disorders: New data and an updated meta-analysis, Schizophrenia Research, 2018-12-01 00:00:00. (Journal).
Published, 12/2018.
https://www.scopus.com/inward/record.uri?partnerID... - Huang W., Quach T.D., Dascalu C., Liu Z., Leung T., Byrne-Steele M., Pan W., Yang Q., Han J., Lesser M., Rothstein T.L., Furie R., Mackay M., Aranow C., Davidson A., Belimumab promotes negative selection of activated autoreactive B cells in systemic lupus erythematosus patients, JCI insight, 2018-09-06 00:00:00. (Journal).
Published, 09/06/2018.
https://www.scopus.com/inward/record.uri?partnerID... - Aziz M., Ode Y., Zhou M., Ochani M., Holodick N., Rothstein T., Wang P., B-1a cells protect mice from sepsis-induced acute lung injury, Molecular Medicine, 2018-05-29 00:00:00. (Journal).
Published, 05/29/2018.
https://www.scopus.com/inward/record.uri?partnerID... - Aziz M., Holodick N., Rothstein T., Wang P., B-1a cells protect mice from sepsis: Critical role of creb, Journal of Immunology, 2017-07-15 00:00:00. (Journal).
Published, 07/15/2017.
https://www.scopus.com/inward/record.uri?partnerID... - Kaku H., Holodick N., Tumang J., Rothstein T., CD25<sup>+</sup> B-1a cells express Aicda, Frontiers in Immunology, 2017-06-20 00:00:00. (Journal).
Published, 06/20/2017.
https://www.scopus.com/inward/record.uri?partnerID... - Quách T., Hopkins T., Holodick N., Vuyyuru R., Manser T., Bayer R., Rothstein T., Human B-1 and B-2 B cells develop from Lin<sup>-</sup>CD34<sup>+</sup>CD38<sup>lo</sup> stem cells, Journal of Immunology, 2016-11-15 00:00:00. (Journal).
Published, 11/15/2016.
https://www.scopus.com/inward/record.uri?partnerID... - Olofsson P., Steinberg B., Sobbi R., Cox M., Ahmed M., Oswald M., Szekeres F., Hanes W., Introini A., Liu S., Holodick N., Rothstein T., Lövdahl C., Chavan S., Yang H., Pavlov V., Broliden K., Andersson U., Diamond B., Miller E., Arner A., Gregersen P., Backx P., Mak T., Tracey K., Blood pressure regulation by CD4<sup>+</sup> lymphocytes expressing choline acetyltransferase, Nature Biotechnology, 2016-10-01 00:00:00. (Journal).
Published, 10/01/2016.
https://www.scopus.com/inward/record.uri?partnerID... - Guo B., Zhang L., Chiorazzi N., Rothstein T.L., IL-4 rescues surface IgM expression in chronic lymphocytic leukemia, Blood, 2016-07-28 00:00:00. (Journal).
Published, 07/28/2016.
https://www.scopus.com/inward/record.uri?partnerID... - Holodick N., Vizconde T., Hopkins T., Rothstein T., Age-related decline in natural igm function: Diversification and selection of the B-1a cell pool with age, Journal of Immunology, 2016-05-15 00:00:00. (Journal).
Published, 05/15/2016.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Holodick N., Activation of B-1 Cells, Encyclopedia of Immunobiology, 2016-04-27 00:00:00. (Book).
Published, 04/27/2016.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Natural antibodies as rheostats for susceptibility to chronic diseases in the aged, Frontiers in Immunology, 2016-04-07 00:00:00. (Journal).
Published, 04/07/2016.
https://www.scopus.com/inward/record.uri?partnerID... - Holodick N.E., Zeumer L., Rothstein T.L., Morel L., Expansion of B-1a cells with germline heavy chain sequence in lupus mice, Frontiers in Immunology, 2016-03-24 00:00:00. (Journal).
Published, 03/24/2016.
https://www.scopus.com/inward/record.uri?partnerID... - Guo B., Rothstein T., RasGRP1 is an essential signaling molecule for development of B1a cells with autoantigen receptors, Journal of Immunology, 2016-03-15 00:00:00. (Journal).
Published, 03/15/2016.
https://www.scopus.com/inward/record.uri?partnerID... - Sharma A., Kiripolsky J., Klimatcheva E., Howell A., Fereidouni F., Levenson R., Rothstein T., Kramer J., Early BAFF receptor blockade mitigates murine Sjögren's syndrome: Concomitant targeting of CXCL13 and the BAFF receptor prevents salivary hypofunction, Clinical Immunology, 2016-03-01 00:00:00. (Journal).
Published, 03/01/2016.
https://www.scopus.com/inward/record.uri?partnerID... - Kramer J.M., Holodick N.E., Vizconde T.C., Raman I., Yan M., Li Q.Z., Gaile D.P., Rothstein T.L., Analysis of IgM antibody production and repertoire in a mouse model of Sjögren’s syndrome, Journal of Leukocyte Biology, 2016-02-01 00:00:00. (Journal).
Published, 02/2016.
https://www.scopus.com/inward/record.uri?partnerID... - Quach T., Rodriguez-Zhurbenko N., Hopkins T., Guo X., Hernandez A., Li W., Rothstein T., Distinctions among circulating antibody-secreting cell populations, including B-1 cells, in human adult peripheral blood, Journal of Immunology, 2016-02-01 00:00:00. (Journal).
Published, 02/01/2016.
https://www.scopus.com/inward/record.uri?partnerID... - Cui X., Zhang L., Magli A., Catera R., Yan X., Griffin D., Rothstein T., Barrientos J., Kolitz J., Allen S., Rai K., Chiorazzi N., Chu C., Cytoplasmic myosin-exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell viability, Leukemia, 2016-01-01 00:00:00. (Journal).
Published, 01/01/2016.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Herzenberg L., Holodick N., Ghosn E., B-1 Cell Development and Function, Annals of the New York Academy of Sciences, 2015-12-01 00:00:00. (Book Series).
Published, 12/01/2015.
https://www.scopus.com/inward/record.uri?partnerID... - Aziz M., Holodick N.E., Rothstein T.L., Wang P., The role of B-1 cells in inflammation, Immunologic Research, 2015-12-01 00:00:00. (Journal).
Published, 12/01/2015.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Quach T., The human counterpart of mouse B-1 cells, Annals of the New York Academy of Sciences, 2015-12-01 00:00:00. (Journal).
Published, 12/01/2015.
https://www.scopus.com/inward/record.uri?partnerID... - Holodick N., Rothstein T., B cells in the aging immune system: Time to consider B-1 cells, Annals of the New York Academy of Sciences, 2015-12-01 00:00:00. (Journal).
Published, 12/01/2015.
https://www.scopus.com/inward/record.uri?partnerID... - Engelbertsen D., Vallejo J., Dan Quách T., Fredrikson G.N., Alm R., Hedblad B., Björkbacka H., Rothstein T.L., Nilsson J., Bengtsson E., Low levels of IgM antibodies against an advanced glycation endproduct-modified apolipoprotein B100 peptide predict cardiovascular events in nondiabetic subjects, Journal of Immunology, 2015-10-01 00:00:00. (Journal).
Published, 10/01/2015.
https://www.scopus.com/inward/record.uri?partnerID... - Husain-Krautter S., Kramer J.M., Li W., Guo B., Rothstein T.L., The osteopontin transgenic mouse is a new model for Sjögren's syndrome, Clinical Immunology, 2015-03-01 00:00:00. (Journal).
Published, 03/01/2015.
https://www.scopus.com/inward/record.uri?partnerID... - Kaku H., Cheng K.F., Al-Abed Y., Rothstein T.L., A novel mechanism of B cell-mediated immune suppression through CD73 expression and adenosine production, Journal of Immunology, 2014-12-15 00:00:00. (Journal).
Published, 12/15/2014.
https://www.scopus.com/inward/record.uri?partnerID... - Weber G., Chousterman B., Hilgendorf I., Robbins C., Theurl I., Gerhardt L., Iwamoto Y., Quach T., Ali M., Chen J., Rothstein T., Nahrendorf M., Weissleder R., Swirski F., Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis, Journal of Experimental Medicine, 2014-06-01 00:00:00. (Journal).
Published, 06/2014.
https://www.scopus.com/inward/record.uri?partnerID... - Holodick N., Vizconde T., Rothstein T., B-1a Cell diversity: Nontemplated addition in B-1a cell ig is determined by progenitor population and developmental location, Journal of Immunology, 2014-03-01 00:00:00. (Journal).
Published, 03/01/2014.
https://www.scopus.com/inward/record.uri?partnerID... - Holodick N., Vizconde T., Rothstein T., Splenic B-1a cells expressing CD138 spontaneously secrete large amounts of immunoglobulin in naïve mice, Frontiers in Immunology, 2014-01-01 00:00:00. (Journal).
Published, 2014.
https://www.scopus.com/inward/record.uri?partnerID... - Kramer J., Klimatcheva E., Rothstein T., CXCL13 is elevated in Sjögren's syndrome in mice and humans and is implicated in disease pathogenesis, Journal of Leukocyte Biology, 2013-11-01 00:00:00. (Journal).
Published, 11/2013.
https://www.scopus.com/inward/record.uri?partnerID... - Guo B., Rothstein T., IL-4 upregulates Igα and Igβ protein, resulting in augmented IgM maturation and B cell receptor-triggered B cell activation, Journal of Immunology, 2013-07-15 00:00:00. (Journal).
Published, 07/15/2013.
https://www.scopus.com/inward/record.uri?partnerID... - Guo B., Rothstein T., A novel Lyn-protein kinase Cδ/ε-protein kinase D axis is activated in B cells by signalosome-independent alternate pathway BCR signaling, European Journal of Immunology, 2013-06-01 00:00:00. (Journal).
Published, 06/2013.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Griffin D., Holodick N., Quach T., Kaku H., Human B-1 cells take the stage, Annals of the New York Academy of Sciences, 2013-05-01 00:00:00. (Book Series).
Published, 05/2013.
https://www.scopus.com/inward/record.uri?partnerID... - Chen S., Batliwalla F., Holodick N., Yan X., Yancopoulos S., Croce C., Rothstein T., Chiorazzi N., Autoantigen can promote progression to a more aggressive TCL1 leukemia by selecting variants with enhanced B-cell receptor signaling, Proceedings of the National Academy of Sciences of the United States of America, 2013-04-16 00:00:00. (Journal).
Published, 04/16/2013.
https://www.scopus.com/inward/record.uri?partnerID... - Li W., Batliwalla F., Rothstein T.L., Human B-1 cells are not preplasmablasts: Analysis of microarray data and other issues, Blood, 2013-01-01 00:00:00. (Journal).
Published, 2013.
https://www.scopus.com/inward/record.uri?partnerID... - Holodick N., Rothstein T., Atypical response of B-1 cells to BCR ligation: A speculative model, Frontiers in Immunology, 2013-01-01 00:00:00. (Journal).
Published, 2013.
https://www.scopus.com/inward/record.uri?partnerID... - Griffin D., Quach T., Batliwalla F., Andreopoulos D., Holodick N., Rothstein T., Human CD11b<sup>+</sup> B1 cells are not monocytes: A reply to "Gene profiling of CD11b<sup>+</sup> and CD11b<sup>-</sup> B1 cell subsets reveals potential cell sorting artifacts", Journal of Experimental Medicine, 2012-03-12 00:00:00. (Journal).
Published, 03/12/2012.
https://www.scopus.com/inward/record.uri?partnerID... - Griffin D.O., Rothstein T.L., Human "orchestrator" CD11b(+) B1 cells spontaneously secrete interleukin-10 and regulate T-cell activity., Molecular medicine (Cambridge, Mass.), 2012-01-01 00:00:00. (Journal).
Published, 2012.
https://www.scopus.com/inward/record.uri?partnerID... - Griffin D., Rothstein T., Human B1 cell frequency: Isolation and analysis of human B1 cells, Frontiers in Immunology, 2012-01-01 00:00:00. (Journal).
Published, 2012.
https://www.scopus.com/inward/record.uri?partnerID... - Wang Y., Rothstein T., Induction of Th17 cell differentiation by B-1 cells, Frontiers in Immunology, 2012-01-01 00:00:00. (Journal).
Published, 2012.
https://www.scopus.com/inward/record.uri?partnerID... - Griffin D.O., Holodick N.E., Rothstein T.L., Human B1 cells are CD3<sup>-</sup>: A reply to "A human equivalent of mouse B-1 cells?" and "The nature of circulating CD27<sup>+</sup>CD43<sup>+</sup> B cells", Journal of Experimental Medicine, 2011-12-19 00:00:00. (Journal).
Published, 12/19/2011.
https://www.scopus.com/inward/record.uri?partnerID... - Griffin D., Rothstein T., A small cd11b <sup>+</sup> human B1 cell subpopulation stimulates T cells and is expanded in lupus, Journal of Experimental Medicine, 2011-12-19 00:00:00. (Journal).
Published, 12/19/2011.
https://www.scopus.com/inward/record.uri?partnerID... - Zhong X., Rothstein T.L., L2pB1: A new player in autoimmunity, Molecular Immunology, 2011-06-01 00:00:00. (Journal).
Published, 06/2011.
https://www.scopus.com/inward/record.uri?partnerID... - Griffin D., Holodick N., Rothstein T., Correction: Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20<sup>+</sup>CD27<sup>+</sup>CD43<sup>+</sup>CD70<sup>-</sup>, Journal of Experimental Medicine, 2011-04-11 00:00:00. (Journal).
Published, 04/11/2011.
https://www.scopus.com/inward/record.uri?partnerID... - Griffin D., Holodick N., Rothstein T., Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20<sup>+</sup>CD27<sup>+</sup>CD43<sup>+</sup>CD70<sup>-</sup> (The Journal of Experimental Medicine (2011), 208, 1, (67-80)), Journal of Experimental Medicine, 2011-02-14 00:00:00. (Journal).
Published, 02/14/2011.
https://www.scopus.com/inward/record.uri?partnerID... - Griffin D., Holodick N., Rothstein T., Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20<sup>+</sup>CD27<sup>+</sup>CD43<sup>+</sup>CD70<sup>-</sup>, Journal of Experimental Medicine, 2011-01-17 00:00:00. (Journal).
Published, 01/17/2011.
https://www.scopus.com/inward/record.uri?partnerID... - Tumang J., Holodick N., Vizconde T., Kaku H., Francés R., Rothstein T., A CD25<sup>-</sup> positive population of activated B1 cells expresses LIFR and responds to LIF, Frontiers in Immunology, 2011-01-01 00:00:00. (Journal).
Published, 2011.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Grand challenges in B cell biology, Frontiers in Immunology, 2011-01-01 00:00:00. (Journal).
Published, 2011.
https://www.scopus.com/inward/record.uri?partnerID... - Kaku H., Rothstein T.L., Fas apoptosis inhibitory molecule enhances CD40 signaling in B cells and augments the plasma cell compartment (Journal of Immunology (2009) 183, (1667-1674)), Journal of Immunology, 2010-07-01 00:00:00. (Journal).
Published, 07/01/2010.
https://www.scopus.com/inward/record.uri?partnerID... - Kaku H., Rothstein T., Octamer binding protein 2 (Oct2) regulates PD-L2 gene expression in B-1 cells through lineage-specific activity of a unique, intronic promoter, Genes and Immunity, 2010-01-01 00:00:00. (Journal).
Published, 01/2010.
https://www.scopus.com/inward/record.uri?partnerID... - Holodick N., Tumang J., Rothstein T., Immunoglobulin secretion by B1 cells: Differential intensity and IRF4-dependence of spontaneous IgM secretion by peritoneal and splenic B1 cells, European Journal of Immunology, 2010-01-01 00:00:00. (Journal).
Published, 2010.
https://www.scopus.com/inward/record.uri?partnerID... - Zhong X., Lau S., Bai C., Degauque N., Holodick N., Steven S., Tumang J., Gao W., Rothstein T., A novel subpopulation of B-1 cells is enriched with autoreactivity in normal and lupus-prone mice, Arthritis and Rheumatism, 2009-12-01 00:00:00. (Journal).
Published, 12/2009.
https://www.scopus.com/inward/record.uri?partnerID... - Kaku H., Rothstein T., Fas apoptosis inhibitory molecule expression in B cells is regulated through IRF4 in a feed-forward mechanism, Journal of Immunology, 2009-11-01 00:00:00. (Journal).
Published, 11/01/2009.
https://www.scopus.com/inward/record.uri?partnerID... - Holodick N., Repetny K., Zhong X., Rothstein T., Adult BM generates CD5<sup>+</sup> B1 cells containing abundant N-region additions, European Journal of Immunology, 2009-09-01 00:00:00. (Journal).
Published, 09/2009.
https://www.scopus.com/inward/record.uri?partnerID... - Holodick N., Tumang J., Rothstein T., Continual signaling is responsible for constitutive ERK phosphorylation in B-1a cells, Molecular Immunology, 2009-09-01 00:00:00. (Journal).
Published, 09/2009.
https://www.scopus.com/inward/record.uri?partnerID... - Kaku H., Rothstein T., Fas apoptosis inhibitory molecule enhances CD40 signaling in B cells and augments the plasma cell compartment, Journal of Immunology, 2009-08-01 00:00:00. (Journal).
Published, 08/01/2009.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Guo B., Receptor crosstalk: Reprogramming B cell receptor signalling to an alternate pathway results in expression and secretion of the autoimmunity-associated cytokine, osteopontin, Journal of Internal Medicine, 2009-06-01 00:00:00. (Journal).
Published, 06/2009.
https://www.scopus.com/inward/record.uri?partnerID... - Repetny K.J., Zhong X., Holodick N.E., Rothstein T.L., Hansen U., Binding of LBP-1a to specific immunoglobulin switch regions in vivo correlates with specific repression of class switch recombination, European Journal of Immunology, 2009-05-01 00:00:00. (Journal).
Published, 05/2009.
https://www.scopus.com/inward/record.uri?partnerID... - Hemond M., Rothstein T.L., Wagner G., Fas Apoptosis Inhibitory Molecule Contains a Novel β-Sandwich in Contact with a Partially Ordered Domain, Journal of Molecular Biology, 2009-03-06 00:00:00. (Journal).
Published, 03/06/2009.
https://www.scopus.com/inward/record.uri?partnerID... - Guo B., Tumang J., Rothstein T., B cell receptor crosstalk: B cells express osteopontin through the combined action of the alternate and classical BCR signaling pathways, Molecular Immunology, 2009-02-01 00:00:00. (Journal).
Published, 02/2009.
https://www.scopus.com/inward/record.uri?partnerID... - Busconi L., Bauer J.W., Tumang J.R., Laws A., Perkins-Mesires K., Tabor A.S., Lau C., Corley R.B., Rothstein T.L., Lund F.E., Behrens T.W., Marshak-Rothstein A., Functional outcome of B cell activation by chromatin immune complex engagement of the B cell receptor and TLR9, Journal of Immunology, 2007-12-01 00:00:00. (Journal).
Published, 12/01/2007.
https://www.scopus.com/inward/record.uri?partnerID... - Zhong X., Gao W., Degauque N., Bai C., Lu Y., Kenny J., Oukka M., Strom T.B., Rothstein T.L., Reciprocal generation of Th1/Th17 and T<inf>reg</inf> cells by B1 and B2 B cells, European Journal of Immunology, 2007-09-01 00:00:00. (Journal).
Published, 09/2007.
https://www.scopus.com/inward/record.uri?partnerID... - Zhong X., Tumang J.R., Gao W., Bai C., Rothstein T., Rothstein T.L., PD-L2 expression extends beyond dendritic cells/macrophages to B1 cells enriched for V<inf>H</inf>11/V<inf>H</inf>12 and phosphatidylcholine binding, European Journal of Immunology, 2007-09-01 00:00:00. (Journal).
Published, 09/2007.
https://www.scopus.com/inward/record.uri?partnerID... - Dye J.R., Palvanov A., Guo B., Rothstein T.L., B cell receptor cross-talk: Exposure to lipopolysaccharide induces an alternate pathway for B cell receptor-induced ERK phosphorylation and NF-κB activation, Journal of Immunology, 2007-07-01 00:00:00. (Journal).
Published, 07/01/2007.
https://www.scopus.com/inward/record.uri?partnerID... - Mineva N.D., Rothstein T.L., Meyers J.A., Lerner A., Sonenshein G.E., CD40 ligand-mediated activation of the de novo RelB NF-κB synthesis pathway in transformed B cells promotes rescue from apoptosis, Journal of Biological Chemistry, 2007-06-15 00:00:00. (Journal).
Published, 06/15/2007.
https://www.scopus.com/inward/record.uri?partnerID... - Guo B., Blair D., Chiles T., Lowell C., Rothstein T., Cutting edge: B cell receptor (BCR) cross-talk: The IL-4-induced alternate pathway for BCR signaling operates in parallel with the classical pathway, is sensitive to rottlerin, and depends on Lyn, Journal of Immunology, 2007-04-15 00:00:00. (Journal).
Published, 04/15/2007.
https://www.scopus.com/inward/record.uri?partnerID... - Francés R., Tumang J.R., Rothstein T.L., Extreme skewing of annexin II and S100A6 expression identified by proteomic analysis of peritoneal B-1 cells, International Immunology, 2007-01-01 00:00:00. (Journal).
Published, 01/2007.
https://www.scopus.com/inward/record.uri?partnerID... - Mataraza J., Tumang J., Gumina M., Gurdak S., Rothstein T., Chiles T., Disruption of cyclin D3 blocks proliferation of normal B-1a cells, but loss of cyclin D3 is compensated by cyclin D2 in cyclin D3-deficient mice, Journal of Immunology, 2006-07-15 00:00:00. (Journal).
Published, 07/15/2006.
https://www.scopus.com/inward/record.uri?partnerID... - Hastings W., Gurdak S., Tumang J., Rothstein T., CD5<sup>+</sup>/Mac-1<sup>-</sup> peritoneal B cells: A novel B cell subset that exhibits characteristics of B-1 cells, Immunology Letters, 2006-05-15 00:00:00. (Journal).
Published, 05/15/2006.
https://www.scopus.com/inward/record.uri?partnerID... - Hastings W., Tumang J., Behrens T., Rothstein T., Peritoneal B-2 cells comprise a distinct B-2 cell population with B-1b-like characteristics, European Journal of Immunology, 2006-05-01 00:00:00. (Journal).
Published, 05/2006.
https://www.scopus.com/inward/record.uri?partnerID... - Francés R., Tumang J., Kaku H., Gurdak S., Rothstein T., B-1 cells express transgelin 2: Unexpected lymphocyte expression of a smooth muscle protein identified by proteomic analysis of peritoneal B-1 cells, Molecular Immunology, 2006-05-01 00:00:00. (Journal).
Published, 05/2006.
https://www.scopus.com/inward/record.uri?partnerID... - Seung G., Tumang J.R., Rothstein T.L., Characteristic features of B cells in murine cervical lymph nodes, Acta Oto-Laryngologica, 2006-01-01 00:00:00. (Journal).
Published, 01/2006.
https://www.scopus.com/inward/record.uri?partnerID... - Rosenbauer F., Owens B.M., Yu L., Tumang J.R., Steidl U., Kutok J.L., Clayton L.K., Wagner K., Scheller M., Iwasaki H., Liu C., Hackanson B., Akashi K., Leutz A., Rothstein T.L., Plass C., Tenen D.G., Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1, Nature Genetics, 2006-01-01 00:00:00. (Journal).
Published, 01/2006.
https://www.scopus.com/inward/record.uri?partnerID... - Barrington R.A., Zhang M., Zhong X., Jonsson H., Holodick N., Cherukuri A., Pierce S.K., Rothstein T.L., Carroll M.C., CD21/CD19 coreceptor signaling promotes B cell survival during primary immune responses, Journal of Immunology, 2005-09-01 00:00:00. (Journal).
Published, 09/01/2005.
https://www.scopus.com/inward/record.uri?partnerID... - Francés R., Tumang J., Rothstein T., Cutting edge: B-1 cells are deficient in Lck: Defective B cell receptor signal transduction in B-1 cells occurs in the absence of elevated Lck expression, Journal of Immunology, 2005-07-01 00:00:00. (Journal).
Published, 07/01/2005.
https://www.scopus.com/inward/record.uri?partnerID... - Mizuno T., Rothstein T.L., B cell receptor (BCR) cross-talk: CD40 engagement creates an alternate pathway for BCR signaling that activates IκB kinase/IκBα/NF- κB without the need for PI3K and phospholipase Cγ, Journal of Immunology, 2005-05-15 00:00:00. (Journal).
Published, 05/15/2005.
https://www.scopus.com/inward/record.uri?partnerID... - Guo B., Rothstein T., B Cell Receptor (BCR) cross-talk: IL-4 creates an alternate pathway for BCR-induced ERK activation that is phosphatidylinositol 3-kinase independent, Journal of Immunology, 2005-05-01 00:00:00. (Journal).
Published, 05/01/2005.
https://www.scopus.com/inward/record.uri?partnerID... - Tumang J.R., Francés R., Yeo S., Rothstein T.L., Cutting edge: Spontaneously Ig-secreting B-1 cells violate the accepted paradigm for expression of differentiation-associated transcription factors, Journal of Immunology, 2005-03-15 00:00:00. (Journal).
Published, 03/15/2005.
https://www.scopus.com/inward/record.uri?partnerID... - Mizuno T., Rothstein T.L., B cell receptor (BCR) cross-talk: CD40 engagement enhances BCR-induced ERK activation, Journal of Immunology, 2005-03-15 00:00:00. (Journal).
Published, 03/15/2005.
https://www.scopus.com/inward/record.uri?partnerID... - Foote L.C., Evans J.W., Cifuni J.M., Siracusa M.C., Monteforte G.M., McCole J.L., D'Orazio C.C., Hastings W.D., Rothstein T.L., Interleukin-4 produces a breakdown of tolerance in vivo with autoantibody formation and tissue damage, Autoimmunity, 2004-12-01 00:00:00. (Journal).
Published, 12/2004.
https://www.scopus.com/inward/record.uri?partnerID... - Tumang J., Hastings W., Bai C., Rothstein T., Peritoneal and splenic B-1 cells are separable by phenotypic, functional, and transcriptomic characteristics, European Journal of Immunology, 2004-08-01 00:00:00. (Journal).
Published, 08/2004.
https://www.scopus.com/inward/record.uri?partnerID... - Zhong X., Chunyan B., Gao W., Strom T.B., Rothstein T.L., Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger, International Immunology, 2004-08-01 00:00:00. (Journal).
Published, 08/2004.
https://www.scopus.com/inward/record.uri?partnerID... - Piatelli M.J., Wardle C., Blois J., Doughty C., Schram B.R., Rothstein T.L., Chiles T.C., Phosphatidylinositol 3-Kinase-Dependent Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase 1/2 and NF-κB Signaling Pathways Are Required for B Cell Antigen Receptor-Mediated Cyclin D2 Induction in Mature B Cells, Journal of Immunology, 2004-03-01 00:00:00. (Journal).
Published, 03/01/2004.
https://www.scopus.com/inward/record.uri?partnerID... - Greenwald R.J., Tumang J.R., Sinha A., Currier N., Cardiff R.D., Rothstein T.L., Faller D.V., Denis G.V., Eμ-BRD2 transgenic mice develop B-cell lymphoma and leukemia, Blood, 2004-02-15 00:00:00. (Journal).
Published, 02/15/2004.
https://www.scopus.com/inward/record.uri?partnerID... - Mizuno T., Zhong X., Rothstein T., Fas-induced apoptosis in B cells, Apoptosis, 2003-10-01 00:00:00. (Journal).
Published, 10/2003.
https://www.scopus.com/inward/record.uri?partnerID... - Mizuno T., Rothstein T.L., Cutting edge: CD40 engagement eliminates the need for Bruton's tyrosine kinase in B cell receptor signaling for NF-κB, Journal of Immunology, 2003-03-15 00:00:00. (Journal).
Published, 03/15/2003.
https://www.scopus.com/inward/record.uri?partnerID... - Schram B.R., Rothstein T.L., NF-κB is required for surface Ig-induced Fas resistance in B cells, Journal of Immunology, 2003-03-15 00:00:00. (Journal).
Published, 03/15/2003.
https://www.scopus.com/inward/record.uri?partnerID... - Piatelli M.J., Tanguay D., Rothstein T.L., Chiles T.C., Cell cycle control mechanisms in b-1 and b-2 lymphoid subsets, Immunologic Research, 2003-01-01 00:00:00. (Journal).
Published, 2003.
https://www.scopus.com/inward/record.uri?partnerID... - Wurster A.L., Rodgers V., White M., Rothstein T.L., Grusby M.J., Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL, Journal of Biological Chemistry, 2002-07-26 00:00:00. (Journal).
Published, 07/26/2002.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Cutting edge commentary: Two B-1 or not to be one, Journal of Immunology, 2002-05-01 00:00:00. (Journal).
Published, 05/01/2002.
https://www.scopus.com/inward/record.uri?partnerID... - Tumang J., Negm R., Solt L., Schneider T., Colarusso T., Hastings W., Woodland R., Rothstein T., BCR engagement induces Fas resistance in primary B cells in the absence of functional Bruton's tyrosine kinase, Journal of Immunology, 2002-03-15 00:00:00. (Journal).
Published, 03/15/2002.
https://www.scopus.com/inward/record.uri?partnerID... - Irigoyen M., Mizuno T., Zhong X., Negm R.S., Schneider T.J., Rothstein T.L., B cell activation leads to upregulated expression of the murine Sik-similar protein gene, Molecular Immunology, 2002-01-01 00:00:00. (Journal).
Published, 2002.
https://www.scopus.com/inward/record.uri?partnerID... - Owyang A.M., Tumang J.R., Schram B., Hsia C.Y., Behrens T.W., Rothstein T.L., Liou H.C., c-Rel is required for the protection of B cells from antigen receptor-mediated, but not fas-mediated, apoptosis, Journal of Immunology, 2001-11-01 00:00:00. (Journal).
Published, 11/01/2001.
https://www.scopus.com/inward/record.uri?partnerID... - Fischer G.M., Solt L.A., Hastings W.D., Yang K., Gerstein R.M., Nikolajczyk B.S., Clarke S.H., Rothstein T.L., Splenic and peritoneal B-1 cells differ in terms of transcriptional and proliferative features that separate peritoneal B-1 from splenic B-2 cells, Cellular Immunology, 2001-10-10 00:00:00. (Journal).
Published, 10/10/2001.
https://www.scopus.com/inward/record.uri?partnerID... - Tanguay D.A., Colarusso T.P., Doughty C., Pavlovic-Ewers S., Rothstein T.L., Chiles T.C., Cutting edge: Differential signaling requirements for activation of assembled cyclin D3-cdk4 complexes in B-1 and B-2 lymphocyte subsets, Journal of Immunology, 2001-04-01 00:00:00. (Journal).
Published, 04/01/2001.
https://www.scopus.com/inward/record.uri?partnerID... - Zhong X., Schneider T.J., Cabral D.S., Donohoe T., Rothstein T.L., An alternatively spliced long form of Fas apoptosis inhibitory molecule (FAIM) with tissue-specific expression in the brain, Molecular Immunology, 2001-01-01 00:00:00. (Journal).
Published, 2001.
https://www.scopus.com/inward/record.uri?partnerID... - Fan H., Rothstein T., Lymphokine dependence of STAT3 activation produced by surface immunoglobulin cross-linking and by phorbol ester plus calcium ionophore treatment in B cells, European Journal of Immunology, 2001-01-01 00:00:00. (Journal).
Published, 2001.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T.L., Inducible resistance to Fas-mediated apoptosis in B cells, Cell Research, 2000-12-01 00:00:00. (Journal).
Published, 12/2000.
https://www.scopus.com/inward/record.uri?partnerID... - Karras J., McKay R., Lu T., Pych J., Frank D., Rothstein T., Monia B., STAT3 regulates the growth and immunoglobulin production of BCL<inf>1</inf> B cell lymphoma through control of cell cycle progression, Cellular Immunology, 2000-06-15 00:00:00. (Journal).
Published, 06/15/2000.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T.L., Fischer G.M., Tanguay D.A., Pavlovic S., Colarusso T.P., Gerstein R.M., Clarke S.H., Chiles T.C., STAT3 activation, chemokine receptor expression, and cyclin-Cdk function in B-1 cells, Current Topics in Microbiology and Immunology, 2000-01-01 00:00:00. (Book Series).
Published, 2000.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T.L., Zhong X., Schram B.R., Negm R.S., Donohoe T., Cabral D.S., Foote L.C., Schneider T.J., Receptor-specific regulation of B-cell susceptibility to Fas-mediated apoptosis and a novel Fas apoptosis inhibitory molecule, Immunological Reviews, 2000-01-01 00:00:00. (Journal).
Published, 2000.
https://www.scopus.com/inward/record.uri?partnerID... - Tanguay D.A., Colarusso T.P., Pavlovic S., Irigoyen M., Howard R.G., Bartek J., Chiles T.C., Rothstein T.L., Early induction of cyclin D2 expression in phorbol ester-responsive B-1 lymphocytes, Journal of Experimental Medicine, 1999-06-07 00:00:00. (Journal).
Published, 06/07/1999.
https://www.scopus.com/inward/record.uri?partnerID... - Schneider T.J., Fischer G.M., Donohoe T.J., Colarusso T.P., Rothstein T.L., A novel gene coding for a Fas apoptosis inhibitory molecule (FAIM) isolated from inducibly Fas-resistant B lymphocytes, Journal of Experimental Medicine, 1999-03-15 00:00:00. (Journal).
Published, 03/15/1999.
https://www.scopus.com/inward/record.uri?partnerID... - Foote L.C., Marshak-Rothstein A., Rothstein T.L., Tolerant B lymphocytes acquire resistance to Fas-mediated apoptosis after treatment with interleukin 4 but not after treatment with specific antigen unless a surface immunoglobulin threshold is exceeded, Journal of Experimental Medicine, 1998-03-16 00:00:00. (Journal).
Published, 03/16/1998.
https://www.scopus.com/inward/record.uri?partnerID... - Francis D.A., Sen R., Rice N., Rothstein T.L., Receptor-specific induction of NF-κB components in primary B cells, International Immunology, 1998-01-01 00:00:00. (Journal).
Published, 1998.
https://www.scopus.com/inward/record.uri?partnerID... - Schneider T.J., Grillot D., Foote L.C., Núñez G.E., Rothstein T.L., Bcl-x Protects Primary B Cells Against Fas- Mediated Apoptosis, Journal of Immunology, 1997-11-15 00:00:00. (Journal).
Published, 11/15/1997.
https://www.scopus.com/inward/record.uri?partnerID... - Karras J.G., Wang Z., Huo L., Frank D.A., Rothstein T.L., Induction of STAT Protein Signaling Through the CD40 Receptor in B Lymphocytes: Distinct STAT Activation Following Surface Ig and CD40 Receptor Engagement, Journal of Immunology, 1997-11-01 00:00:00. (Journal).
Published, 11/01/1997.
https://www.scopus.com/inward/record.uri?partnerID... - Wang Z., Karras J., Colarusso T., Foote L., Rothstein T., Unmethylated CpG motifs protect murine B lymphocytes against Fas- mediated apoptosis, Cellular Immunology, 1997-09-15 00:00:00. (Journal).
Published, 09/15/1997.
https://www.scopus.com/inward/record.uri?partnerID... - Fine A., Anderson N.L., Rothstein T.L., Williams M.C., Gochuico B.R., Fas expression in pulmonary alveolar type II cells, American Journal of Physiology - Lung Cellular and Molecular Physiology, 1997-07-01 00:00:00. (Journal).
Published, 07/1997.
https://www.scopus.com/inward/record.uri?partnerID... - Karras J.G., Wang Z., Huo L., Howard R.G., Frank D.A., Rothstein T.L., Signal transducer and activator of transcription-3 (STAT3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes, Journal of Experimental Medicine, 1997-03-17 00:00:00. (Journal).
Published, 03/17/1997.
https://www.scopus.com/inward/record.uri?partnerID... - Jacobson B., Foote L., Panka D., Ju S., Rothstein T., Marshak-Rothstein A., Unique site of autoantibody production in Fas-deficient mice, Annals of the New York Academy of Sciences, 1997-01-01 00:00:00. (Book Series).
Published, 1997.
https://www.scopus.com/inward/record.uri?partnerID... - Foote L., Marshak-Rothstein A., Rothstein T., Inducible Fas-resistance mediated by IL-4 in activated B cells, Annals of the New York Academy of Sciences, 1997-01-01 00:00:00. (Book Series).
Published, 1997.
https://www.scopus.com/inward/record.uri?partnerID... - Francis D.A., Sen R., Rothstein T.L., Receptor-specific regulation of NF-κB, c-Myc and Fas-mediated apoptosis in primary B cells, Current Topics in Microbiology and Immunology, 1997-01-01 00:00:00. (Book Series).
Published, 1997.
https://www.scopus.com/inward/record.uri?partnerID... - Jacobson B., Rothstein T., Marshak-Rothstein A., Unique site of IgG2a and rheumatoid factor production in MRL/lpr mice, Immunological Reviews, 1997-01-01 00:00:00. (Journal).
Published, 1997.
https://www.scopus.com/inward/record.uri?partnerID... - Huo L., Rothstein T.L., Isolation and Characterization of Murine fra-1: Induction Mediated by CD40 and Surface Ig Is Protein Kinase C Dependent, Journal of Immunology, 1996-11-01 00:00:00. (Journal).
Published, 11/01/1996.
https://www.scopus.com/inward/record.uri?partnerID... - Jacobson B., Rothstein T., Marshak-Rothstein A., The role of Fas/FasL interactions in the regulation of B cell function., Behring Institute Mitteilungen, 1996-10-01 00:00:00. (Journal).
Published, 10/1996.
https://www.scopus.com/inward/record.uri?partnerID... - Foote L.C., Howard R.G., Marshak-Rothstein A., Rothstein T.L., IL-4 Induces Fas Resistance in B Cells, Journal of Immunology, 1996-10-01 00:00:00. (Journal).
Published, 10/01/1996.
https://www.scopus.com/inward/record.uri?partnerID... - Karras J.G., Huo L., Wang Z., Frank D.A., Zimmet J.M., Rothstein T.L., Delayed Tyrosine Phosphorylation and Nuclear Expression of STAT1 Following Antigen Receptor Stimulation of B Lymphocytes, Journal of Immunology, 1996-09-15 00:00:00. (Journal).
Published, 09/15/1996.
https://www.scopus.com/inward/record.uri?partnerID... - Wu M., Lee H., Bellas R.E., Schauer S.L., Arsura M., Katz D., Fitzgerald M., Rothstein T.L., Sherr D., Sonenshein G.E., Inhibition of NF-κB/Rel induces apoptosis of murine B cells, EMBO Journal, 1996-09-02 00:00:00. (Journal).
Published, 09/02/1996.
https://www.scopus.com/inward/record.uri?partnerID... - Foote L.C., Schneider T.J., Fischer G.M., Wang J.K.M., Rasmussen B., Campbell K., Lynch D.H., Ju S.T., Marshak-Rothstein A., Rothstein T.L., Intracellular Signaling for Inducible Antigen Receptor-Mediated Fas Resistance in B Cells, Journal of Immunology, 1996-09-01 00:00:00. (Journal).
Published, 09/01/1996.
https://www.scopus.com/inward/record.uri?partnerID... - Fischer M.B., Ma M., Goerg S., Zhou X., Xia J., Finco O., Han S., Kelsoe G., Howard R.G., Rothstein T.L., Kremmer E., Rosen F.S., Carroll M.C., Regulation of the B cell response to T-dependent antigens by classical pathway complement, Journal of Immunology, 1996-07-15 00:00:00. (Journal).
Published, 07/15/1996.
https://www.scopus.com/inward/record.uri?partnerID... - Karras J.G., Wang Z., Coniglio S.J., Frank D.A., Rothstein T.L., Antigen-receptor engagement in B cells induces nuclear expression of STAT5 and STAT6 proteins that bind and transactivate an IFN-γ activation site, Journal of Immunology, 1996-07-01 00:00:00. (Journal).
Published, 07/01/1996.
https://www.scopus.com/inward/record.uri?partnerID... - Schauer S., Wang Z., Sonenshein G., Rothstein T., Maintenance of nuclear factor-κB/Rel and c-myc expression during CD40 ligand rescue of WEHI 231 early B cells from receptor-mediated apoptosis through modulation of IκB proteins, Journal of Immunology, 1996-07-01 00:00:00. (Journal).
Published, 07/01/1996.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Signals and susceptibility to programmed death in B cells, Current Opinion in Immunology, 1996-06-01 00:00:00. (Journal).
Published, 06/1996.
https://www.scopus.com/inward/record.uri?partnerID... - Xie H., Wang Z., Rothstein T.L., Signaling pathways for antigen receptor-mediated induction of transcription factor CREB in B lymphocytes, Cellular Immunology, 1996-05-01 00:00:00. (Journal).
Published, 05/01/1996.
https://www.scopus.com/inward/record.uri?partnerID... - Ahearn J.M., Fischer M.B., Croix D., Goerg S., Ma M., Xia J., Zhou X., Howard R.G., Rothstein T.L., Carroll M.C., Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen, Immunity, 1996-03-01 00:00:00. (Journal).
Published, 03/1996.
https://www.scopus.com/inward/record.uri?partnerID... - Ozdemirli M., El-Khatib M., Foote L.C., Wang J.K.M., Marshak-Rothstein A., Rothstein T.L., Ju S.T., Fas (CD95)/Fas ligand interactions regulate antigen-specific, major histocompatibility complex-restricted T/B cell proliferative responses, European Journal of Immunology, 1996-02-01 00:00:00. (Journal).
Published, 02/1996.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T.L., Foote L.C., Schneider T.J., Fischer G.M., Jacobson B.A., Lynch D.H., Ju S.T., Marshak-Rothstein A., Inducible resistance to Fas-mediated apoptosis in primary B lymphocytes, Advances in Experimental Medicine and Biology, 1996-01-01 00:00:00. (Book Series).
Published, 1996.
https://www.scopus.com/inward/record.uri?partnerID... - Schauer S.L., Wang Z., Wu M., Arsura M., Lee H., Sherr D., Rothstein T.L., Sonenshein G.E., Maintenance of NF-KB/rel and c-myc expression through modulation of 1kb proteins during CD40 ligand rescue of WEHI 231 B, FASEB Journal, 1996-01-01 00:00:00. (Journal).
Published, 1996.
https://www.scopus.com/inward/record.uri?partnerID... - Wang Z., Morris D.L., Rothstein T.L., Constitutive and inducible levels of egr-1 and c-myc early growth response gene expression in self-renewing B-1 lymphocytes, Cellular Immunology, 1995-05-01 00:00:00. (Journal).
Published, 05/1995.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T.L., Wang J.K.M., Panka D.J., Foote L.C., Wang Z., Stanger B., Cui H., Ju S.T., Marshak-Rothstein A., Protection against Fas-dependent Thl-mediated apoptosis by antigen receptor engagement in B cells, Nature, 1995-03-09 00:00:00. (Journal).
Published, 03/09/1995.
https://www.scopus.com/inward/record.uri?partnerID... - Francis D.A., Karras J.G., Ke X., Sen R., Rothstein T.L., Induction of the transcription factors NF-κB, AP-1 and NF-AT during B cell stimulation through the CD40 receptor, International Immunology, 1995-02-01 00:00:00. (Journal).
Published, 02/1995.
https://www.scopus.com/inward/record.uri?partnerID... - Dziennis S., Van Etten R.A., Pahl H.L., Morris D.L., Rothstein T.L., Blosch C., Perlmutter R.M., Tenen D.G., The CD11b promoter directs high-level expression of reporter genes in macrophages in transgenic mice, Blood, 1995-01-15 00:00:00. (Journal).
Published, 01/15/1995.
https://www.scopus.com/inward/record.uri?partnerID... - Xie H., Rothstein T.L., Protein kinase C mediates activation of nuclear cAMP response element- binding protein (CREB) in B lymphocytes stimulated through surface Ig, Journal of Immunology, 1995-01-01 00:00:00. (Journal).
Published, 1995.
https://www.scopus.com/inward/record.uri?partnerID... - Huo L., Rothstein T., Receptor-specific induction of individual AP-1 components in B lymphocytes, Journal of Immunology, 1995-01-01 00:00:00. (Journal).
Published, 1995.
https://www.scopus.com/inward/record.uri?partnerID... - Wang Z., Karras J., Howard R., Rothstein T., Induction of bcl-x by CD40 engagement rescues sIg-induced apoptosis in murine B cells, Journal of Immunology, 1995-01-01 00:00:00. (Journal).
Published, 1995.
https://www.scopus.com/inward/record.uri?partnerID... - Morris D., Rothstein T., Analysis of b-1 cell activation, Methods: A Companion to Methods in Enzymology, 1995-01-01 00:00:00. (Journal).
Published, 01/01/1995.
https://www.scopus.com/inward/record.uri?partnerID... - Tanguay D., Tanguay J., McManus B., Huo L., Rothstein T., Chiles T., Activation of AP-1 in primary B lymphocytes by surface immunoglobulin requires de novo Jun-B synthesis, Cellular Immunology, 1994-10-01 00:00:00. (Journal).
Published, 10/1994.
https://www.scopus.com/inward/record.uri?partnerID... - Morris D., Rothstein T., Decreased surface IgM receptor-mediated activation of phospholipase C<inf>γ</inf>2 in B-1 lymphocytes, International Immunology, 1994-07-01 00:00:00. (Journal).
Published, 07/1994.
https://www.scopus.com/inward/record.uri?partnerID... - Venkataraman L., Francis D.A., Wang Z., Liu J., Rothstein T.L., Sen R., Cyclosporin-a sensitive induction of NF-AT in murine B cells, Immunity, 1994-06-01 00:00:00. (Journal).
Published, 06/1994.
https://www.scopus.com/inward/record.uri?partnerID... - Huo L., Chung W., Rothstein T., C-terminal sequence of the NF-κB p50 precursor from primary murine B-lymphocytes, Gene, 1994-02-25 00:00:00. (Journal).
Published, 02/25/1994.
https://www.scopus.com/inward/record.uri?partnerID... - Lalmanach-Girard A.C., Chiles T.C., Parker D.C., Rothstein T.L., T cell-dependent induction of NF-κB in B cells, Journal of Experimental Medicine, 1993-04-01 00:00:00. (Journal).
Published, 04/01/1993.
https://www.scopus.com/inward/record.uri?partnerID... - Liu J., Sen R., Rothstein T., Abnormal κB-binding protein in the cytoplasm of a plasmacytoma cell line that lacks nuclear expression of NF-κB, Molecular Immunology, 1993-04-01 00:00:00. (Journal).
Published, 04/1993.
https://www.scopus.com/inward/record.uri?partnerID... - Morris D., Rothstein T., Abnormal transcription factor induction through the surface immunoglobulin M receptor of B-1 lymphocytes, Journal of Experimental Medicine, 1993-03-01 00:00:00. (Journal).
Published, 03/01/1993.
https://www.scopus.com/inward/record.uri?partnerID... - Xie H., Chiles T.C., Rothstein T.L., Induction of CREB activity via the surface Ig receptor of B cells, Journal of Immunology, 1993-01-01 00:00:00. (Journal).
Published, 1993.
https://www.scopus.com/inward/record.uri?partnerID... - Wieselthier J.S., Japowicz M.C., Rothstein T.L., Yu T.L., Anderson T., Koh H., Inefficacy of extracorporeal photochemotherapy in the treatment of B‐Cell chronic lymphocytic leukemia: Preliminary results, American Journal of Hematology, 1992-10-01 00:00:00. (Journal).
Published, 10/1992.
https://www.scopus.com/inward/record.uri?partnerID... - ROTHSTEIN T., KOLBER D., COHEN D., CD5‐like Phorbol‐Ester Responsiveness in Conventional B Cells Activated through Surface Immunoglobulin, Annals of the New York Academy of Sciences, 1992-05-01 00:00:00. (Book Series).
Published, 05/1992.
https://www.scopus.com/inward/record.uri?partnerID... - Chiles T.C., Rothstein T.L., Surface Ig receptor-induced nuclear AP-1-dependent gene expression in B lymphocytes, Journal of Immunology, 1992-01-01 00:00:00. (Journal).
Published, 1992.
https://www.scopus.com/inward/record.uri?partnerID... - Kolber D.L., Rothstein T.L., Shultz L.D., Phorbol ester responsiveness of murine Ly‐1‐lineage B cells from normal and viable motheaten mutant mice, European Journal of Immunology, 1991-03-01 00:00:00. (Journal).
Published, 03/1991.
https://www.scopus.com/inward/record.uri?partnerID... - Tilzey J., Chiles T.C., Rothstein T.L., Jun-B gene expression mediated by the surface immunoglobulin receptor of primary B lymphocytes, Biochemical and Biophysical Research Communications, 1991-02-28 00:00:00. (Journal).
Published, 02/28/1991.
https://www.scopus.com/inward/record.uri?partnerID... - Liu J., Chiles T., Sen R., Rothstein T., Inducible nuclear expression of NF-κB in primary B cells stimulated through the surface Ig receptor, Journal of Immunology, 1991-01-01 00:00:00. (Journal).
Published, 1991.
https://www.scopus.com/inward/record.uri?partnerID... - Chiles T.C., Liu J., Rothstein T.L., Cross-linking of surface Ig receptors on murine B lymphocytes stimulates the expression of nuclear tetradecanoyl phorbol acetate-response element-binding proteins, Journal of Immunology, 1991-01-01 00:00:00. (Journal).
Published, 1991.
https://www.scopus.com/inward/record.uri?partnerID... - Cohen D., Rothstein T., Elevated levels of protein kinase C activity and α-isoenzyme expression in murine peritoneal B cells, Journal of Immunology, 1991-01-01 00:00:00. (Journal).
Published, 1991.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T.L., Kolber D.L., Murphy T.P., Cohen D.P., Induction of phorbol ester responsiveness in conventional B cells after activation via surface Ig, Journal of Immunology, 1991-01-01 00:00:00. (Journal).
Published, 1991.
https://www.scopus.com/inward/record.uri?partnerID... - Murphy T., Kolber D., Rothstein T., Elevated expression of Pgp‐1 (Ly‐24) by murine peritoneal B lymphocytes, European Journal of Immunology, 1990-05-01 00:00:00. (Journal).
Published, 05/1990.
https://www.scopus.com/inward/record.uri?partnerID... - Miller P., Pothoulakis C., Baeker T., LaMont J., Rothstein T., Macrophage-dependent stimulation of T cell-depleted spleen cells by Clostridium difficile toxin A and calcium ionophore, Cellular Immunology, 1990-03-01 00:00:00. (Journal).
Published, 03/1990.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T.L., Polyreactive low-affinity IgM antibodies produced by CD5+B cells, Immunology Today, 1990-01-01 00:00:00. (Journal).
Published, 1990.
https://www.scopus.com/inward/record.uri?partnerID... - Buckler A.J., Rothstein T.L., Sonenshein G.E., Transcriptional control of c-myc gene expression during stimulation of murine B lymphocytes, Journal of Immunology, 1990-01-01 00:00:00. (Journal).
Published, 1990.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Polyreactive low-affinity IgM antibodies produced by CD5+B cells, Trends in Immunology, 1990-01-01 00:00:00. (Journal).
Published, 1990.
https://www.scopus.com/inward/record.uri?partnerID... - Wolfowicz C.B., Lyons S., Mahon C.A., Marshak-Rothstein A., Rothstein T.L., Isolation of self-recognizing IgG2a monoclonal rheumatoid factors, Clinical Immunology and Immunopathology, 1989-08-01 00:00:00. (Journal).
Published, 08/1989.
https://www.scopus.com/inward/record.uri?partnerID... - van Haelst-Pisani C., Cragoe E., Rothstein T., Cytoplasmic alkalinization produced by the combination of anti-immunoglobulin antibody plus cytochalasin D in murine B lymphocytes, Experimental Cell Research, 1989-07-01 00:00:00. (Journal).
Published, 07/1989.
https://www.scopus.com/inward/record.uri?partnerID... - Cohen D.P., Rothstein T.L., Adenosine 3′,5′-cyclic monophosphate modulates the mitogenic responses of murine B lymphocytes, Cellular Immunology, 1989-06-01 00:00:00. (Journal).
Published, 06/1989.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Interleukin-4 enhances peritoneal B cell stimulation induced by phorbol ester, Cellular Immunology, 1989-05-01 00:00:00. (Journal).
Published, 05/1989.
https://www.scopus.com/inward/record.uri?partnerID... - Wolfowicz C.B., Sakorafas P., Rothstein T.L., Marshak-Rothstein A., Oligoclonality of rheumatoid factors arising spontaneously in lpr/lpr mice, Clinical Immunology and Immunopathology, 1988-03-01 00:00:00. (Journal).
Published, 03/1988.
https://www.scopus.com/inward/record.uri?partnerID... - Shlomchik M.J., Marshak-Rothstein A., Wolfowicz C.B., Rothstein T.L., Weigert M.G., The role of clonal selection and somatic mutation in autoimmunity, Nature, 1988-01-01 00:00:00. (Journal).
Published, 1988.
https://www.scopus.com/inward/record.uri?partnerID... - Buckler A.J., Kessler D.J., Duyao M.P., Rothstein T.L., Sonenshein G.E., Regulation of c-myc gene transcription in B lymphocytes: mechanisms of negative and positive control., Current topics in microbiology and immunology, 1988-01-01 00:00:00. (Journal).
Published, 1988.
https://www.scopus.com/inward/record.uri?partnerID... - Van Haelst C., Rothstein T., Cytochalasin stimulates phosphoinositide metabolism in murine B lymphocytes, Journal of Immunology, 1988-01-01 00:00:00. (Journal).
Published, 1988.
https://www.scopus.com/inward/record.uri?partnerID... - Buckler A., Rothstein T., Sonenshein G., Two-step stimulation of B lymphocytes to enter DNA synthesis: Synergy between anti-immunoglobulin antibody and cytochalasin on expression of c-myc and a G<inf>1</inf>-specific gene, Molecular and Cellular Biology, 1988-01-01 00:00:00. (Journal).
Published, 1988.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Kolber D., Peritoneal B cells respond to phorbol esters in the absence of co-mitogen, Journal of Immunology, 1988-01-01 00:00:00. (Journal).
Published, 1988.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Kolber D., Anti-Ig antibody inhibits the phorbol ester-induced stimulation of peritoneal B cells, Journal of Immunology, 1988-01-01 00:00:00. (Journal).
Published, 1988.
https://www.scopus.com/inward/record.uri?partnerID... - ROTHSTEIN T., KOLBER D., Two Dual‐Signal Pathways for Stimulation of B Cells Mediated by Calcium Ionophores, Annals of the New York Academy of Sciences, 1987-05-01 00:00:00. (Book Series).
Published, 05/1987.
https://www.scopus.com/inward/record.uri?partnerID... - Baeker T.R., Simons E.R., Rothstein T.L., Cytochalasin induces an increase in cytosolic free calcium in murine B lymphocytes, Journal of Immunology, 1987-01-01 00:00:00. (Journal).
Published, 1987.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T.L., Kolber D.L., Simons E.R., Baeker T.R., Inhibition by phorbol esters of antiimmunoglobulin induced calcium signalling and B‐cell activation, Journal of Cellular Physiology, 1986-12-01 00:00:00. (Journal).
Published, 12/1986.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T.L., Baeker T.R., Miller R.A., Kolber D.L., Stimulation of murine B cells by the combination of calcium ionophore plus phorbol ester, Cellular Immunology, 1986-10-15 00:00:00. (Journal).
Published, 10/15/1986.
https://www.scopus.com/inward/record.uri?partnerID... - Baeker T.R., Rothstein T.L., Effects of anti-IgM on mitogen-induced proliferation of human B-lymphocyte malignancies, Clinical Immunology and Immunopathology, 1986-05-01 00:00:00. (Journal).
Published, 05/1986.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Stimulation of B cells by sequential addition of anti-immunoglobulin antibody and cytochalasin, Journal of Immunology, 1986-01-01 00:00:00. (Journal).
Published, 1986.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Stimulation of normal but not xid-defective B cells by calcium ionophore and cytochalasin, Journal of Immunology, 1986-01-01 00:00:00. (Journal).
Published, 1986.
https://www.scopus.com/inward/record.uri?partnerID... - Weissman D., Rothstein T., Marshak-Rothstein A., Growing xenogenic monoclonals in murine ascites, Federation Proceedings, 1985-01-01 00:00:00. (Journal).
Published, 1985.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T.L., Anti-immunoglobulin in combination with cytochalasin stimulates proliferation of murine B lymphocytes, Journal of Immunology, 1985-01-01 00:00:00. (Journal).
Published, 1985.
https://www.scopus.com/inward/record.uri?partnerID... - Weissman D., Parker D.J., Rothstein T.L., Marshak-Rothstein A., Methods for the production of xenogeneic monoclonal antibodies in murine ascites, Journal of Immunology, 1985-01-01 00:00:00. (Journal).
Published, 1985.
https://www.scopus.com/inward/record.uri?partnerID... - Weissman D., Rothstein T.L., Marshak-Rothstein A., A rapid method for comparing monoclonal antibodies by limited proteolysis and electrophoresis, Hybridoma, 1985-01-01 00:00:00. (Journal).
Published, 1985.
https://www.scopus.com/inward/record.uri?partnerID... - Baeker T.R., Rothstein T.L., Proliferation of human malignant lymphocytes induced by anti-IgM independent of B cell growth factor, Journal of Immunology, 1985-01-01 00:00:00. (Journal).
Published, 1985.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T.L., Miller R.A., Parker D.J., Kelly E., Paul Vastola A., Marshak-Rothstein A., Induction of idiotope suppression in the anti-azophenylarsonate response of T-depleted A/J mice, Journal of Experimental Medicine, 1984-04-01 00:00:00. (Journal).
Published, 04/01/1984.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T.L., Vastola A., Homologous monoclonal antibodies induce idiotope-specific suppression in neonates through maternal influence and in adults exposed during fetal and neonatal life, Journal of Immunology, 1984-01-01 00:00:00. (Journal).
Published, 1984.
https://www.scopus.com/inward/record.uri?partnerID... - MARGOLIES M.N., JUSZCZAK E.C., NEAR R., MARSHAK‐ROTHSTEIN A., ROTHSTEIN T.L., SATO V.L., SIEKEVITZ M., SMITH J., WYSOCKI L.J., GEFTER M.L., Structural Correlates of Idiotypy in the Arsonate System, Annals of the New York Academy of Sciences, 1983-12-01 00:00:00. (Book Series).
Published, 12/1983.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Gefter M., Affinity analysis of idiotype-positive and idiotype-negative Ars-binding hybridoma proteins and Ars-immune sera, Molecular Immunology, 1983-02-01 00:00:00. (Journal).
Published, 02/1983.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Margolies M., Gefter M., Marshak-Rothstein A., Fine specificity of idiotope suppression in the a/j anti-azophenylarsonate response, Journal of Experimental Medicine, 1983-02-01 00:00:00. (Journal).
Published, 02/01/1983.
https://www.scopus.com/inward/record.uri?partnerID... - Mond J., Mage M., Rothstein T., Mosier D., Herrod H., Asofsky R., Paul W., High anti-TNP plaque-forming cell potential of residual mIg <sup>+</sup> cells in a T cell population, Journal of Immunology, 1980-01-01 00:00:00. (Journal).
Published, 1980.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T.L., Mage M., Jones G., McHugh L.L., Cytotoxic T lymphocyte sequential killing of immobilized allogeneic tumor target cells measured by time-lapse microcinematography, Journal of Immunology, 1978-01-01 00:00:00. (Journal).
Published, 1978.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Mage M., Mond J., McHugh L., Guinea pig antiserum to mouse cytotoxic T lymphocytes and their precursors, Journal of Immunology, 1978-01-01 00:00:00. (Journal).
Published, 1978.
https://www.scopus.com/inward/record.uri?partnerID... - Mage M., McHugh L., Rothstein T., Mouse lymphocytes with and without surface immunoglobulin: Preparative scale separation in polystyrene tissue culture dishes coated with specifically purified anti-immunoglobulin, Journal of Immunological Methods, 1977-03-01 00:00:00. (Journal).
Published, 03/1977.
https://www.scopus.com/inward/record.uri?partnerID... - Mage M., McHugh L., Rothstein T., Separation of graft versus host antigen reactive cells in vitro, Transplantation Proceedings, 1976-01-01 00:00:00. (Journal).
Published, 1976.
https://www.scopus.com/inward/record.uri?partnerID... - Blum J., Rothstein T., Lysosomes in Tetrahymena., Frontiers of biology, 1975-01-01 00:00:00. (Journal).
Published, 1975.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Blum J., Lysosomal physiology in tetrahym en A: III. pharmacological studies on acid hydrolase release and the ingestion and egestion of dimethylbenzanthracene particles, Journal of Cell Biology, 1974-09-01 00:00:00. (Journal).
Published, 09/01/1974.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Blum J., Lysosomal physiology in Tetrahymena. IV. Effect of dichloroisoproterenol on the intracellular source of released acid hydrolases, Experimental Cell Research, 1974-07-01 00:00:00. (Journal).
Published, 07/1974.
https://www.scopus.com/inward/record.uri?partnerID... - ROTHSTEIN T., BLUM J., Lysosomal Physiology in Tetrahymena. II. Effect of Culture Age and Temperature on the Extracellular Release of 3 Acid Hydrolases, The Journal of Protozoology, 1974-02-01 00:00:00. (Journal).
Published, 02/1974.
https://www.scopus.com/inward/record.uri?partnerID... - Rothstein T., Blum J., Lysosomal physiology in tetrahymena: I. effect of glucose, acetate, pyruvate, and carmine on intracellular content and extracellular release of three acid hydrolases, Journal of Cell Biology, 1973-06-01 00:00:00. (Journal).
Published, 06/01/1973.
https://www.scopus.com/inward/record.uri?partnerID...
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