Thomas L Rothstein, MD, PhD

Thomas L Rothstein, MD, PhD portrait
  • Professor, Department of Biomedical Sciences
    • Primary Address
    • Office
    • Western Michigan University Homer Stryker M.D. School of Medicine
    • 1000 Oakland Drive
    • Kalamazoo, MI,  49008

Publications

Publications

  • Huang W, Quach TD, Dascalu C, Liu Z, Leung T, Byrne-Steele M, Pan W, Yang Q, Han J, Lesser M, Rothstein TL, Furie R, Mackay M, Aranow C, Davidson A, Belimumab promotes negative selection of activated autoreactive B cells in systemic lupus erythematosus patients., JCI insight, 2018-09-06 00:00:00. (Journal Article). Ahead of print, 09/06/2018.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=30185675
  • Gallego JA, Blanco EA, Husain-Krautter S, Madeline Fagen E, Moreno-Merino P, Del Ojo-Jiménez JA, Ahmed A, Rothstein TL, Lencz T, Malhotra AK, Cytokines in cerebrospinal fluid of patients with schizophrenia spectrum disorders: New data and an updated meta-analysis., Schizophrenia research, 2018-07-16 00:00:00. (Journal Article). Ahead of print, 07/16/2018.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=30025760
  • Aziz M, Ode Y, Zhou M, Ochani M, Holodick NE, Rothstein TL, Wang P, B-1a cells protect mice from sepsis-induced acute lung injury., Molecular medicine (Cambridge, Mass.), 2018-05-29 00:00:00. (Journal Article). E-published, 05/29/2018.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=30134811
  • Aziz M, Holodick NE, Rothstein TL, Wang P, Aziz M., Holodick N., Rothstein T., Wang P., B-1a Cells Protect Mice from Sepsis: Critical Role of CREB., Journal of immunology (Baltimore, Md. : 1950), 2017-07-15 00:00:00. (Journal Article , Journal). Published, 07/15/2017.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=28630091
  • Kaku H., Holodick N., Tumang J., Rothstein T., CD25+B-1a cells express Aicda, Frontiers in Immunology, 2017-06-20 00:00:00. (Journal). Published, 06/20/2017.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000081
  • Kaku H, Holodick NE, Tumang JR, Rothstein TL, CD25 + B-1a Cells Express Aicda., Frontiers in immunology, 2017-01-01 00:00:00. (Journal Article). Published, 2017.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=28676801
  • Quách TD, Hopkins TJ, Holodick NE, Vuyyuru R, Manser T, Bayer RL, Rothstein TL, Quách T., Hopkins T., Holodick N., Vuyyuru R., Manser T., Bayer R., Rothstein T., Human B-1 and B-2 B Cells Develop from Lin-CD34+CD38lo Stem Cells., Journal of immunology (Baltimore, Md. : 1950), 2016-11-15 00:00:00. (Journal Article , Journal). Published, 11/15/2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=27815443
  • Olofsson PS, Steinberg BE, Sobbi R, Cox MA, Ahmed MN, Oswald M, Szekeres F, Hanes WM, Introini A, Liu SF, Holodick NE, Rothstein TL, Lövdahl C, Chavan SS, Yang H, Pavlov VA, Broliden K, Andersson U, Diamond B, Miller EJ, Arner A, Gregersen PK, Backx PH, Mak TW, Tracey KJ, Olofsson P., Steinberg B., Sobbi R., Cox M., Ahmed M., Oswald M., Szekeres F., Hanes W., Introini A., Liu S., Holodick N., Rothstein T., Lövdahl C., Chavan S., Yang H., Pavlov V., Broliden K., Andersson U., Diamond B., Miller E., Arner A., Gregersen P., Backx P., Mak T., Tracey K., Blood pressure regulation by CD4+ lymphocytes expressing choline acetyltransferase., Nature biotechnology, 2016-10-01 00:00:00. (Journal Article , Journal). Published, 10/01/2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=27617738
  • Guo B, Zhang L, Chiorazzi N, Rothstein TL, Guo B., Zhang L., Chiorazzi N., Rothstein T., IL-4 rescues surface IgM expression in chronic lymphocytic leukemia., Blood, 2016-07-28 00:00:00. (Journal Article , Journal). Published, 07/28/2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=27226435
  • Holodick NE, Vizconde T, Hopkins TJ, Rothstein TL, Holodick N., Vizconde T., Hopkins T., Rothstein T., Age-Related Decline in Natural IgM Function: Diversification and Selection of the B-1a Cell Pool with Age., Journal of immunology (Baltimore, Md. : 1950), 2016-05-15 00:00:00. (Journal Article , Journal). Published, 05/15/2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=27183643
  • Rothstein T., Holodick N., Activation of B-1 Cells, Encyclopedia of Immunobiology, 2016-04-27 00:00:00. (Book). Published, 04/27/2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000082
  • Rothstein T., Natural antibodies as rheostats for susceptibility to chronic diseases in the aged, Frontiers in Immunology, 2016-04-07 00:00:00. (Journal). Published, 04/07/2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000123
  • Holodick N., Zeumer L., Rothstein T., Morel L., Expansion of B-1a cells with germline heavy chain sequence in lupus mice, Frontiers in Immunology, 2016-03-24 00:00:00. (Journal). Published, 03/24/2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000083
  • Guo B, Rothstein TL, Guo B., Rothstein T., RasGRP1 Is an Essential Signaling Molecule for Development of B1a Cells with Autoantigen Receptors., Journal of immunology (Baltimore, Md. : 1950), 2016-03-15 00:00:00. (Journal Article , Journal). Published, 03/15/2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=26851222
  • Sharma A, Kiripolsky J, Klimatcheva E, Howell A, Fereidouni F, Levenson R, Rothstein TL, Kramer JM, Sharma A., Kiripolsky J., Klimatcheva E., Howell A., Fereidouni F., Levenson R., Rothstein T., Kramer J., Early BAFF receptor blockade mitigates murine Sjögren's syndrome: Concomitant targeting of CXCL13 and the BAFF receptor prevents salivary hypofunction., Clinical immunology (Orlando, Fla.), 2016-03-01 00:00:00. (Journal Article , Journal). Published, 03/01/2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=26826598
  • Kramer JM, Holodick NE, Vizconde TC, Raman I, Yan M, Li QZ, Gaile DP, Rothstein TL, Kramer J., Holodick N., Vizconde T., Raman I., Yan M., Li Q., Gaile D., Rothstein T., Analysis of IgM antibody production and repertoire in a mouse model of Sjögren's syndrome., Journal of leukocyte biology, 2016-02-01 00:00:00. (Journal Article , Journal). Published, 02/2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=26382297
  • Quách TD, Rodríguez-Zhurbenko N, Hopkins TJ, Guo X, Hernández AM, Li W, Rothstein TL, Quach T., Rodriguez-Zhurbenko N., Hopkins T., Guo X., Hernandez A., Li W., Rothstein T., Distinctions among Circulating Antibody-Secreting Cell Populations, Including B-1 Cells, in Human Adult Peripheral Blood., Journal of immunology (Baltimore, Md. : 1950), 2016-02-01 00:00:00. (Journal Article , Journal). Published, 02/01/2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=26740107
  • Holodick NE, Zeumer L, Rothstein TL, Morel L, Expansion of B-1a Cells with Germline Heavy Chain Sequence in Lupus Mice., Frontiers in immunology, 2016-01-01 00:00:00. (Journal Article). Published, 2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=27047495
  • Rothstein TL, Natural Antibodies as Rheostats for Susceptibility to Chronic Diseases in the Aged., Frontiers in immunology, 2016-01-01 00:00:00. (Journal Article , Review). Published, 2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=27092140
  • Cui X, Zhang L, Magli AR, Catera R, Yan XJ, Griffin DO, Rothstein TL, Barrientos J, Kolitz JE, Allen SL, Rai KR, Chiorazzi N, Chu CC, Cui X., Zhang L., Magli A., Catera R., Yan X., Griffin D., Rothstein T., Barrientos J., Kolitz J., Allen S., Rai K., Chiorazzi N., Chu C., Cytoplasmic myosin-exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell viability., Leukemia, 2016-01-01 00:00:00. (Journal Article , Journal). Published, 01/01/2016.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=26220042
  • Rothstein TL, Herzenberg LA, Holodick NE, Ghosn E, Rothstein T., Herzenberg L., Holodick N., Ghosn E., B-1 Cell Development and Function., Annals of the New York Academy of Sciences, 2015-12-01 00:00:00. (Book Series). Published, 12/01/2015.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=26662722
  • Aziz M, Holodick NE, Rothstein TL, Wang P, Aziz M., Holodick N., Rothstein T., Wang P., The role of B-1 cells in inflammation., Immunologic research, 2015-12-01 00:00:00. (Journal Article , Review , Journal). Published, 12/01/2015.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=26427372
  • Rothstein TL, Quach TD, Rothstein T., Quach T., The human counterpart of mouse B-1 cells., Annals of the New York Academy of Sciences, 2015-12-01 00:00:00. (Journal Article , Review , Journal). Published, 12/01/2015.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=25988790
  • Holodick NE, Rothstein TL, Holodick N., Rothstein T., B cells in the aging immune system: time to consider B-1 cells., Annals of the New York Academy of Sciences, 2015-12-01 00:00:00. (Journal Article , Review , Journal). Published, 12/01/2015.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=26194480
  • Engelbertsen D, Vallejo J, Quách TD, Fredrikson GN, Alm R, Hedblad B, Björkbacka H, Rothstein TL, Nilsson J, Bengtsson E, Engelbertsen D., Vallejo J., Dan Quách T., Fredrikson G., Alm R., Hedblad B., Björkbacka H., Rothstein T., Nilsson J., Bengtsson E., Low Levels of IgM Antibodies against an Advanced Glycation Endproduct-Modified Apolipoprotein B100 Peptide Predict Cardiovascular Events in Nondiabetic Subjects., Journal of immunology (Baltimore, Md. : 1950), 2015-10-01 00:00:00. (Journal Article , Journal). Published, 10/01/2015.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=26290603
  • Husain-Krautter S, Kramer JM, Li W, Guo B, Rothstein TL, Husain-Krautter S., Kramer J., Li W., Guo B., Rothstein T., The osteopontin transgenic mouse is a new model for Sjögren's syndrome., Clinical immunology (Orlando, Fla.), 2015-03-01 00:00:00. (Journal Article , Journal). Published, 03/01/2015.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=25572532
  • Kaku H, Cheng KF, Al-Abed Y, Rothstein TL, Kaku H., Cheng K., Al-Abed Y., Rothstein T., A novel mechanism of B cell-mediated immune suppression through CD73 expression and adenosine production., Journal of immunology (Baltimore, Md. : 1950), 2014-12-15 00:00:00. (Journal Article , Journal). Published, 12/15/2014.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=25392527
  • Weber GF, Chousterman BG, Hilgendorf I, Robbins CS, Theurl I, Gerhardt LM, Iwamoto Y, Quach TD, Ali M, Chen JW, Rothstein TL, Nahrendorf M, Weissleder R, Swirski FK, Weber G., Chousterman B., Hilgendorf I., Robbins C., Theurl I., Gerhardt L., Iwamoto Y., Quach T., Ali M., Chen J., Rothstein T., Nahrendorf M., Weissleder R., Swirski F., Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis., The Journal of experimental medicine, 2014-06-02 00:00:00. (Journal Article , Journal). Published, 06/2014.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=24821911
  • Holodick NE, Vizconde T, Rothstein TL, Holodick N., Vizconde T., Rothstein T., B-1a cell diversity: nontemplated addition in B-1a cell Ig is determined by progenitor population and developmental location., Journal of immunology (Baltimore, Md. : 1950), 2014-03-01 00:00:00. (Journal Article , Journal). Published, 03/01/2014.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=24477911
  • Holodick NE, Vizconde T, Rothstein TL, Splenic B-1a Cells Expressing CD138 Spontaneously Secrete Large Amounts of Immunoglobulin in Naïve Mice., Frontiers in immunology, 2014-01-01 00:00:00. (Journal Article). Published, 2014.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=24734034
  • Holodick N., Vizconde T., Rothstein T., Splenic B-1a cells expressing CD138 spontaneously secrete large amounts of immunoglobulin in naïve mice, Frontiers in Immunology, 2014-01-01 00:00:00. (Journal). Published, 2014.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000084
  • Holodick NE, Rothstein TL, Atypical Response of B-1 Cells to BCR Ligation: A Speculative Model., Frontiers in immunology, 2013-12-16 00:00:00. (Journal Article , Review). E-published, 12/16/2013.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=24379817
  • Kramer JM, Klimatcheva E, Rothstein TL, Kramer J., Klimatcheva E., Rothstein T., CXCL13 is elevated in Sjögren's syndrome in mice and humans and is implicated in disease pathogenesis., Journal of leukocyte biology, 2013-11-01 00:00:00. (Journal Article , Journal). Published, 11/2013.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=23904442
  • Guo B, Rothstein TL, Guo B., Rothstein T., IL-4 upregulates Igα and Igβ protein, resulting in augmented IgM maturation and B cell receptor-triggered B cell activation., Journal of immunology (Baltimore, Md. : 1950), 2013-07-15 00:00:00. (Journal Article , Journal). Published, 07/15/2013.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=23776171
  • Guo B, Rothstein TL, Guo B., Rothstein T., A novel Lyn-protein kinase Cδ/ε-protein kinase D axis is activated in B cells by signalosome-independent alternate pathway BCR signaling., European journal of immunology, 2013-06-01 00:00:00. (Journal Article , Journal). Published, 06/2013.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=23457006
  • Rothstein TL, Griffin DO, Holodick NE, Quach TD, Kaku H, Human B-1 cells take the stage., Annals of the New York Academy of Sciences, 2013-05-01 00:00:00. (Journal Article , Review). Published, 05/2013.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=23692567
  • Rothstein T., Griffin D., Holodick N., Quach T., Kaku H., Human B-1 cells take the stage, Annals of the New York Academy of Sciences, 2013-05-01 00:00:00. (Book Series). Published, 05/2013.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000086
  • Chen SS, Batliwalla F, Holodick NE, Yan XJ, Yancopoulos S, Croce CM, Rothstein TL, Chiorazzi N, Chen S., Batliwalla F., Holodick N., Yan X., Yancopoulos S., Croce C., Rothstein T., Chiorazzi N., Autoantigen can promote progression to a more aggressive TCL1 leukemia by selecting variants with enhanced B-cell receptor signaling., Proceedings of the National Academy of Sciences of the United States of America, 2013-04-16 00:00:00. (Journal Article , Journal). Published, 04/16/2013.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=23550156
  • Li W, Batliwalla F, Rothstein TL, Li W., Batliwalla F., Rothstein T., Human B-1 cells are not preplasmablasts: analysis of microarray data and other issues., Blood, 2013-11-21 00:00:00. (Comment , Letter , Journal). Published, 2013.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=24263958
  • Holodick N., Rothstein T., Atypical response of B-1 cells to BCR ligation: A speculative model, Frontiers in Immunology, 2013-01-01 00:00:00. (Journal). Published, 2013.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000085
  • Griffin DO, Quach T, Batliwalla F, Andreopoulos D, Holodick NE, Rothstein TL, Griffin D., Quach T., Batliwalla F., Andreopoulos D., Holodick N., Rothstein T., Human CD11b+ B1 cells are not monocytes: A reply to "Gene profiling of CD11b+ and CD11b- B1 cell subsets reveals potential cell sorting artifacts"., The Journal of experimental medicine, 2012-03-12 00:00:00. (Comment , Journal Article , Journal). Published, 03/12/2012.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=22412176
  • Griffin DO, Rothstein TL, Human b1 cell frequency: isolation and analysis of human b1 cells., Frontiers in immunology, 2012-01-01 00:00:00. (Journal Article). Published, 2012.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=22654880
  • Wang Y, Rothstein TL, Induction of Th17 cell differentiation by B-1 cells., Frontiers in immunology, 2012-01-01 00:00:00. (Journal Article). Published, 2012.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=22973276
  • Griffin DO, Rothstein TL, Griffin D., Rothstein T., Human "orchestrator" CD11b(+) B1 cells spontaneously secrete interleukin-10 and regulate T-cell activity., Molecular medicine (Cambridge, Mass.), 2012-09-07 00:00:00. (Journal Article , Journal). Published, 2012.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=22634719
  • Griffin D., Rothstein T., Human B1 cell frequency: Isolation and analysis of human B1 cells, Frontiers in Immunology, 2012-01-01 00:00:00. (Journal). Published, 2012.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000124
  • Wang Y., Rothstein T., Induction of Th17 cell differentiation by B-1 cells, Frontiers in Immunology, 2012-01-01 00:00:00. (Journal). Published, 2012.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000125
  • Griffin DO, Holodick NE, Rothstein TL, Griffin D., Holodick N., Rothstein T., Human B1 cells are CD3-: A reply to "A human equivalent of mouse B-1 cells?" and "The nature of circulating CD27+CD43+ B cells"., The Journal of experimental medicine, 2011-12-19 00:00:00. (Comment , Journal Article , Journal). Published, 12/19/2011.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=22184682
  • Griffin DO, Rothstein TL, Griffin D., Rothstein T., A small CD11b(+) human B1 cell subpopulation stimulates T cells and is expanded in lupus., The Journal of experimental medicine, 2011-12-19 00:00:00. (Clinical Trial , Journal Article , Multicenter Study , Journal). Published, 12/19/2011.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=22110167
  • Zhong X, Rothstein TL, Zhong X., Rothstein T., L2pB1: a new player in autoimmunity., Molecular immunology, 2011-06-01 00:00:00. (Journal Article , Review , Journal). Published, 06/2011.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=21195478
  • Griffin D., Holodick N., Rothstein T., Correction: Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70-, Journal of Experimental Medicine, 2011-04-11 00:00:00. (Journal). Published, 04/11/2011.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000088
  • Griffin D., Holodick N., Rothstein T., Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70-(The Journal of Experimental Medicine (2011), 208, 1, (67-80)), Journal of Experimental Medicine, 2011-02-14 00:00:00. (Journal). Published, 02/14/2011.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000089
  • Griffin DO, Holodick NE, Rothstein TL, Griffin D., Holodick N., Rothstein T., Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+ CD27+ CD43+ CD70-., The Journal of experimental medicine, 2011-01-17 00:00:00. (Journal Article , Journal). Published, 01/17/2011.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=21220451
  • Rothstein TL, Grand challenges in B cell biology., Frontiers in immunology, 2011-01-01 00:00:00. (Journal Article). Published, 2011.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=22566793
  • Tumang JR, Holodick NE, Vizconde TC, Kaku H, Francés R, Rothstein TL, A CD25⁻ positive population of activated B1 cells expresses LIFR and responds to LIF., Frontiers in immunology, 2011-01-01 00:00:00. (Journal Article). Published, 2011.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=22566797
  • Tumang J., Holodick N., Vizconde T., Kaku H., Francés R., Rothstein T., A CD25-positive population of activated B1 cells expresses LIFR and responds to LIF, Frontiers in Immunology, 2011-01-01 00:00:00. (Journal). Published, 2011.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000087
  • Rothstein T., Grand challenges in B cell biology, Frontiers in Immunology, 2011-01-01 00:00:00. (Journal). Published, 2011.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000126
  • Kaku H., Rothstein T., Fas apoptosis inhibitory molecule enhances CD40 signaling in B cells and augments the plasma cell compartment (Journal of Immunology (2009) 183, (1667-1674)), Journal of Immunology, 2010-07-01 00:00:00. (Journal). Published, 07/01/2010.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000127
  • Kaku H, Rothstein TL, Kaku H., Rothstein T., Octamer binding protein 2 (Oct2) regulates PD-L2 gene expression in B-1 cells through lineage-specific activity of a unique, intronic promoter., Genes and immunity, 2010-01-01 00:00:00. (Journal Article , Journal). Published, 01/2010.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=19710692
  • Holodick NE, Tumang JR, Rothstein TL, Holodick N., Tumang J., Rothstein T., Immunoglobulin secretion by B1 cells: differential intensity and IRF4-dependence of spontaneous IgM secretion by peritoneal and splenic B1 cells., European journal of immunology, 2010-11-01 00:00:00. (Journal Article , Journal). Published, 2010.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=21061433
  • Zhong X, Lau S, Bai C, Degauque N, Holodick NE, Steven SJ, Tumang J, Gao W, Rothstein TL, Zhong X., Lau S., Bai C., Degauque N., Holodick N., Steven S., Tumang J., Gao W., Rothstein T., A novel subpopulation of B-1 cells is enriched with autoreactivity in normal and lupus-prone mice., Arthritis and rheumatism, 2009-12-01 00:00:00. (Journal Article , Journal). Published, 12/2009.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=19950285
  • Kaku H, Rothstein TL, Kaku H., Rothstein T., Fas apoptosis inhibitory molecule expression in B cells is regulated through IRF4 in a feed-forward mechanism., Journal of immunology (Baltimore, Md. : 1950), 2009-11-01 00:00:00. (Journal Article , Journal). Published, 11/01/2009.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=19843941
  • Holodick NE, Repetny K, Zhong X, Rothstein TL, Holodick N., Repetny K., Zhong X., Rothstein T., Adult BM generates CD5+ B1 cells containing abundant N-region additions., European journal of immunology, 2009-09-01 00:00:00. (Journal Article , Journal). Published, 09/2009.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=19714574
  • Holodick NE, Tumang JR, Rothstein TL, Holodick N., Tumang J., Rothstein T., Continual signaling is responsible for constitutive ERK phosphorylation in B-1a cells., Molecular immunology, 2009-09-01 00:00:00. (Journal Article , Journal). Published, 09/2009.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=19592097
  • Kaku H, Rothstein TL, Kaku H., Rothstein T., Fas apoptosis inhibitory molecule enhances CD40 signaling in B cells and augments the plasma cell compartment., Journal of immunology (Baltimore, Md. : 1950), 2009-08-01 00:00:00. (Journal Article , Journal). Published, 08/01/2009.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=19592656
  • Rothstein TL, Guo B, Rothstein T., Guo B., Receptor crosstalk: reprogramming B cell receptor signalling to an alternate pathway results in expression and secretion of the autoimmunity-associated cytokine, osteopontin., Journal of internal medicine, 2009-06-01 00:00:00. (Journal Article , Review , Journal). Published, 06/2009.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=19493057
  • Repetny KJ, Zhong X, Holodick NE, Rothstein TL, Hansen U, Repetny K., Zhong X., Holodick N., Rothstein T., Hansen U., Binding of LBP-1a to specific immunoglobulin switch regions in vivo correlates with specific repression of class switch recombination., European journal of immunology, 2009-05-01 00:00:00. (Journal Article , Journal). Published, 05/2009.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=19384868
  • Hemond M, Rothstein TL, Wagner G, Hemond M., Rothstein T., Wagner G., Fas apoptosis inhibitory molecule contains a novel beta-sandwich in contact with a partially ordered domain., Journal of molecular biology, 2009-03-06 00:00:00. (Journal Article , Journal). Published, 03/06/2009.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=19168072
  • Guo B, Tumang JR, Rothstein TL, Guo B., Tumang J., Rothstein T., B cell receptor crosstalk: B cells express osteopontin through the combined action of the alternate and classical BCR signaling pathways., Molecular immunology, 2009-02-01 00:00:00. (Journal Article , Journal). Published, 02/2009.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=18952291
  • Busconi L, Bauer JW, Tumang JR, Laws A, Perkins-Mesires K, Tabor AS, Lau C, Corley RB, Rothstein TL, Lund FE, Behrens TW, Marshak-Rothstein A, Busconi L., Bauer J., Tumang J., Laws A., Perkins-Mesires K., Tabor A., Lau C., Corley R., Rothstein T., Lund F., Behrens T., Marshak-Rothstein A., Functional outcome of B cell activation by chromatin immune complex engagement of the B cell receptor and TLR9., Journal of immunology (Baltimore, Md. : 1950), 2007-12-01 00:00:00. (Journal Article , Journal). Published, 12/01/2007.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=18025183
  • Zhong X, Gao W, Degauque N, Bai C, Lu Y, Kenny J, Oukka M, Strom TB, Rothstein TL, Zhong X., Gao W., Degauque N., Bai C., Lu Y., Kenny J., Oukka M., Strom T., Rothstein T., Reciprocal generation of Th1/Th17 and T(reg) cells by B1 and B2 B cells., European journal of immunology, 2007-09-01 00:00:00. (Journal Article , Journal). Published, 09/2007.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=17683116
  • Zhong X, Tumang JR, Gao W, Bai C, Rothstein TL, Zhong X., Tumang J., Gao W., Bai C., Rothstein T., PD-L2 expression extends beyond dendritic cells/macrophages to B1 cells enriched for V(H)11/V(H)12 and phosphatidylcholine binding., European journal of immunology, 2007-09-01 00:00:00. (Journal Article , Journal). Published, 09/2007.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=17683117
  • Dye JR, Palvanov A, Guo B, Rothstein TL, Dye J., Palvanov A., Guo B., Rothstein T., B cell receptor cross-talk: exposure to lipopolysaccharide induces an alternate pathway for B cell receptor-induced ERK phosphorylation and NF-kappa B activation., Journal of immunology (Baltimore, Md. : 1950), 2007-07-01 00:00:00. (Journal Article , Journal). Published, 07/01/2007.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=17579042
  • Mineva ND, Rothstein TL, Meyers JA, Lerner A, Sonenshein GE, Mineva N., Rothstein T., Meyers J., Lerner A., Sonenshein G., CD40 ligand-mediated activation of the de novo RelB NF-kappaB synthesis pathway in transformed B cells promotes rescue from apoptosis., The Journal of biological chemistry, 2007-06-15 00:00:00. (Journal Article , Journal). Published, 06/15/2007.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=17446175
  • Guo B, Blair D, Chiles TC, Lowell CA, Rothstein TL, Guo B., Blair D., Chiles T., Lowell C., Rothstein T., Cutting Edge: B cell receptor (BCR) cross-talk: the IL-4-induced alternate pathway for BCR signaling operates in parallel with the classical pathway, is sensitive to Rottlerin, and depends on Lyn., Journal of immunology (Baltimore, Md. : 1950), 2007-04-15 00:00:00. (Journal Article , Journal). Published, 04/15/2007.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=17404251
  • Francés R, Tumang JR, Rothstein TL, Francés R., Tumang J., Rothstein T., Extreme skewing of annexin II and S100A6 expression identified by proteomic analysis of peritoneal B-1 cells., International immunology, 2007-01-01 00:00:00. (Journal Article , Journal). Published, 01/2007.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=17135445
  • Mataraza JM, Tumang JR, Gumina MR, Gurdak SM, Rothstein TL, Chiles TC, Mataraza J., Tumang J., Gumina M., Gurdak S., Rothstein T., Chiles T., Disruption of cyclin D3 blocks proliferation of normal B-1a cells, but loss of cyclin D3 is compensated by cyclin D2 in cyclin D3-deficient mice., Journal of immunology (Baltimore, Md. : 1950), 2006-07-15 00:00:00. (Journal Article , Journal). Published, 07/15/2006.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=16818732
  • Hastings WD, Gurdak SM, Tumang JR, Rothstein TL, Hastings W., Gurdak S., Tumang J., Rothstein T., CD5+/Mac-1- peritoneal B cells: a novel B cell subset that exhibits characteristics of B-1 cells., Immunology letters, 2006-05-15 00:00:00. (Journal Article , Journal). Published, 05/15/2006.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=16481048
  • Hastings WD, Tumang JR, Behrens TW, Rothstein TL, Hastings W., Tumang J., Behrens T., Rothstein T., Peritoneal B-2 cells comprise a distinct B-2 cell population with B-1b-like characteristics., European journal of immunology, 2006-05-01 00:00:00. (Journal Article , Journal). Published, 05/2006.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=16609926
  • Francés R, Tumang JR, Kaku H, Gurdak SM, Rothstein TL, Francés R., Tumang J., Kaku H., Gurdak S., Rothstein T., B-1 cells express transgelin 2: unexpected lymphocyte expression of a smooth muscle protein identified by proteomic analysis of peritoneal B-1 cells., Molecular immunology, 2006-05-01 00:00:00. (Journal Article , Journal). Published, 05/2006.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=16487589
  • Yeo SG, Tumang JR, Rothstein TL, Seung G., Tumang J., Rothstein T., Characteristic features of B cells in murine cervical lymph nodes., Acta oto-laryngologica, 2006-01-01 00:00:00. (Journal Article , Journal). Published, 01/2006.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=16308256
  • Rosenbauer F, Owens BM, Yu L, Tumang JR, Steidl U, Kutok JL, Clayton LK, Wagner K, Scheller M, Iwasaki H, Liu C, Hackanson B, Akashi K, Leutz A, Rothstein TL, Plass C, Tenen DG, Rosenbauer F., Owens B., Yu L., Tumang J., Steidl U., Kutok J., Clayton L., Wagner K., Scheller M., Iwasaki H., Liu C., Hackanson B., Akashi K., Leutz A., Rothstein T., Plass C., Tenen D., Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1., Nature genetics, 2006-01-01 00:00:00. (Journal Article , Journal). Published, 01/2006.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=16311598
  • Barrington RA, Zhang M, Zhong X, Jonsson H, Holodick N, Cherukuri A, Pierce SK, Rothstein TL, Carroll MC, Barrington R., Zhang M., Zhong X., Jonsson H., Holodick N., Cherukuri A., Pierce S., Rothstein T., Carroll M., CD21/CD19 coreceptor signaling promotes B cell survival during primary immune responses., Journal of immunology (Baltimore, Md. : 1950), 2005-09-01 00:00:00. (Journal Article , Journal). Published, 09/01/2005.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=16116172
  • Francés R, Tumang JR, Rothstein TL, Francés R., Tumang J., Rothstein T., B-1 cells are deficient in Lck: defective B cell receptor signal transduction in B-1 cells occurs in the absence of elevated Lck expression., Journal of immunology (Baltimore, Md. : 1950), 2005-07-01 00:00:00. (Journal Article , Journal). Published, 07/01/2005.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=15972627
  • Mizuno T, Rothstein TL, Mizuno T., Rothstein T., B cell receptor (BCR) cross-talk: CD40 engagement creates an alternate pathway for BCR signaling that activates I kappa B kinase/I kappa B alpha/NF-kappa B without the need for PI3K and phospholipase C gamma., Journal of immunology (Baltimore, Md. : 1950), 2005-05-15 00:00:00. (Journal Article , Journal). Published, 05/15/2005.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=15879100
  • Guo B, Rothstein TL, Guo B., Rothstein T., B cell receptor (BCR) cross-talk: IL-4 creates an alternate pathway for BCR-induced ERK activation that is phosphatidylinositol 3-kinase independent., Journal of immunology (Baltimore, Md. : 1950), 2005-05-01 00:00:00. (Journal Article , Journal). Published, 05/01/2005.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=15843535
  • Tumang JR, Francés R, Yeo SG, Rothstein TL, Tumang J., Francés R., Yeo S., Rothstein T., Spontaneously Ig-secreting B-1 cells violate the accepted paradigm for expression of differentiation-associated transcription factors., Journal of immunology (Baltimore, Md. : 1950), 2005-03-15 00:00:00. (Journal Article , Journal). Published, 03/15/2005.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=15749846
  • Mizuno T, Rothstein TL, Mizuno T., Rothstein T., B cell receptor (BCR) cross-talk: CD40 engagement enhances BCR-induced ERK activation., Journal of immunology (Baltimore, Md. : 1950), 2005-03-15 00:00:00. (Journal Article , Journal). Published, 03/15/2005.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=15749869
  • Foote LC, Evans JW, Cifuni JM, Siracusa MC, Monteforte GM, McCole JL, D'Orazio CC, Hastings WD, Rothstein TL, Foote L., Evans J., Cifuni J., Siracusa M., Monteforte G., McCole J., D'Orazio C., Hastings W., Rothstein T., Interleukin-4 produces a breakdown of tolerance in vivo with autoantibody formation and tissue damage., Autoimmunity, 2004-12-01 00:00:00. (Journal Article , Journal). Published, 12/2004.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=15763919
  • Tumang JR, Hastings WD, Bai C, Rothstein TL, Tumang J., Hastings W., Bai C., Rothstein T., Peritoneal and splenic B-1 cells are separable by phenotypic, functional, and transcriptomic characteristics., European journal of immunology, 2004-08-01 00:00:00. (Journal Article , Journal). Published, 08/2004.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=15259013
  • Zhong X, Bai C, Gao W, Strom TB, Rothstein TL, Zhong X., Chunyan B., Gao W., Strom T., Rothstein T., Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger., International immunology, 2004-08-01 00:00:00. (Journal Article , Journal). Published, 08/2004.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=15237109
  • Piatelli MJ, Wardle C, Blois J, Doughty C, Schram BR, Rothstein TL, Chiles TC, Piatelli M., Wardle C., Blois J., Doughty C., Schram B., Rothstein T., Chiles T., Phosphatidylinositol 3-kinase-dependent mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 and NF-kappa B signaling pathways are required for B cell antigen receptor-mediated cyclin D2 induction in mature B cells., Journal of immunology (Baltimore, Md. : 1950), 2004-03-01 00:00:00. (Journal Article , Journal). Published, 03/01/2004.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=14978074
  • Greenwald RJ, Tumang JR, Sinha A, Currier N, Cardiff RD, Rothstein TL, Faller DV, Denis GV, Greenwald R., Tumang J., Sinha A., Currier N., Cardiff R., Rothstein T., Faller D., Denis G., E mu-BRD2 transgenic mice develop B-cell lymphoma and leukemia., Blood, 2004-02-15 00:00:00. (Journal Article , Journal). Published, 02/15/2004.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=14563639
  • Mizuno T, Zhong X, Rothstein TL, Mizuno T., Zhong X., Rothstein T., Fas-induced apoptosis in B cells., Apoptosis : an international journal on programmed cell death, 2003-10-01 00:00:00. (Journal Article , Review , Journal). Published, 10/2003.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=12975576
  • Mizuno T, Rothstein TL, Mizuno T., Rothstein T., Cutting edge: CD40 engagement eliminates the need for Bruton's tyrosine kinase in B cell receptor signaling for NF-kappa B., Journal of immunology (Baltimore, Md. : 1950), 2003-03-15 00:00:00. (Journal Article , Journal). Published, 03/15/2003.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=12626529
  • Schram BR, Rothstein TL, Schram B., Rothstein T., NF-kappa B is required for surface Ig-induced Fas resistance in B cells., Journal of immunology (Baltimore, Md. : 1950), 2003-03-15 00:00:00. (Journal Article , Journal). Published, 03/15/2003.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=12626568
  • Piatelli M, Tanguay D, Rothstein T, Chiles T, Piatelli M., Tanguay D., Rothstein T., Chiles T., Cell cycle control mechanisms in B-1 and B-2 lymphoid subsets., Immunologic research, 2003-01-01 00:00:00. (Journal Article , Review , Journal). Published, 2003.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=12637767
  • Wurster AL, Rodgers VL, White MF, Rothstein TL, Grusby MJ, Wurster A., Rodgers V., White M., Rothstein T., Grusby M., Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL., The Journal of biological chemistry, 2002-07-26 00:00:00. (Journal Article , Journal). Published, 07/26/2002.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=12023955
  • Rothstein TL, Rothstein T., Cutting edge commentary: two B-1 or not to be one., Journal of immunology (Baltimore, Md. : 1950), 2002-05-01 00:00:00. (Journal Article , Journal). Published, 05/01/2002.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=11970963
  • Tumang JR, Negm RS, Solt LA, Schneider TJ, Colarusso TP, Hastings WD, Woodland RT, Rothstein TL, Tumang J., Negm R., Solt L., Schneider T., Colarusso T., Hastings W., Woodland R., Rothstein T., BCR engagement induces Fas resistance in primary B cells in the absence of functional Bruton's tyrosine kinase., Journal of immunology (Baltimore, Md. : 1950), 2002-03-15 00:00:00. (Journal Article , Journal). Published, 03/15/2002.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=11884437
  • Irigoyen M, Mizuno T, Zhong X, Negm RS, Schneider TJ, Rothstein TL, Irigoyen M., Mizuno T., Zhong X., Negm R., Schneider T., Rothstein T., B cell activation leads to upregulated expression of the murine Sik-similar protein gene., Molecular immunology, 2002-03-01 00:00:00. (Journal Article , Journal). Published, 2002.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=11922944
  • Owyang AM, Tumang JR, Schram BR, Hsia CY, Behrens TW, Rothstein TL, Liou HC, Owyang A., Tumang J., Schram B., Hsia C., Behrens T., Rothstein T., Liou H., c-Rel is required for the protection of B cells from antigen receptor-mediated, but not Fas-mediated, apoptosis., Journal of immunology (Baltimore, Md. : 1950), 2001-11-01 00:00:00. (Journal Article , Journal). Published, 11/01/2001.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=11673501
  • Fischer GM, Solt LA, Hastings WD, Yang K, Gerstein RM, Nikolajczyk BS, Clarke SH, Rothstein TL, Fischer G., Solt L., Hastings W., Yang K., Gerstein R., Nikolajczyk B., Clarke S., Rothstein T., Splenic and peritoneal B-1 cells differ in terms of transcriptional and proliferative features that separate peritoneal B-1 from splenic B-2 cells., Cellular immunology, 2001-10-10 00:00:00. (Journal Article , Journal). Published, 10/10/2001.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=11747357
  • Tanguay DA, Colarusso TP, Doughty C, Pavlovic-Ewers S, Rothstein TL, Chiles TC, Tanguay D., Colarusso T., Doughty C., Pavlovic-Ewers S., Rothstein T., Chiles T., Cutting edge: differential signaling requirements for activation of assembled cyclin D3-cdk4 complexes in B-1 and B-2 lymphocyte subsets., Journal of immunology (Baltimore, Md. : 1950), 2001-04-01 00:00:00. (Journal Article , Journal). Published, 04/01/2001.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=11254678
  • Zhong X, Schneider TJ, Cabral DS, Donohoe TJ, Rothstein TL, Zhong X., Schneider T., Cabral D., Donohoe T., Rothstein T., An alternatively spliced long form of Fas apoptosis inhibitory molecule (FAIM) with tissue-specific expression in the brain., Molecular immunology, 2001-01-01 00:00:00. (Journal Article , Journal). Published, 2001.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=11483211
  • Fan H, Rothstein TL, Fan H., Rothstein T., Lymphokine dependence of STAT3 activation produced by surface immunoglobulin cross-linking and by phorbol ester plus calcium ionophore treatment in B cells., European journal of immunology, 2001-02-01 00:00:00. (Journal Article , Journal). Published, 2001.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=11180132
  • Rothstein TL, Rothstein T., Inducible resistance to Fas-mediated apoptosis in B cells., Cell research, 2000-12-01 00:00:00. (Journal Article , Review , Journal). Published, 12/2000.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=11191348
  • Karras JG, McKay RA, Lu T, Pych J, Frank DA, Rothstein TL, Monia BP, Karras J., McKay R., Lu T., Pych J., Frank D., Rothstein T., Monia B., STAT3 regulates the growth and immunoglobulin production of BCL(1) B cell lymphoma through control of cell cycle progression., Cellular immunology, 2000-06-15 00:00:00. (Journal Article , Journal). Published, 06/15/2000.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=10896772
  • Rothstein TL, Fischer GM, Tanguay DA, Pavlovic S, Colarusso TP, Gerstein RM, Clarke SH, Chiles TC, Rothstein T., Fischer G., Tanguay D., Pavlovic S., Colarusso T., Gerstein R., Clarke S., Chiles T., STAT3 activation, chemokine receptor expression, and cyclin-Cdk function in B-1 cells., Current topics in microbiology and immunology, 2000-01-01 00:00:00. (Journal Article , Book Series). Published, 2000.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=11125469
  • Rothstein TL, Zhong X, Schram BR, Negm RS, Donohoe TJ, Cabral DS, Foote LC, Schneider TJ, Rothstein T., Zhong X., Schram B., Negm R., Donohoe T., Cabral D., Foote L., Schneider T., Receptor-specific regulation of B-cell susceptibility to Fas-mediated apoptosis and a novel Fas apoptosis inhibitory molecule., Immunological reviews, 2000-08-01 00:00:00. (Journal Article , Review , Journal). Published, 2000.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=11043772
  • Tanguay DA, Colarusso TP, Pavlovic S, Irigoyen M, Howard RG, Bartek J, Chiles TC, Rothstein TL, Tanguay D., Colarusso T., Pavlovic S., Irigoyen M., Howard R., Bartek J., Chiles T., Rothstein T., Early induction of cyclin D2 expression in phorbol ester-responsive B-1 lymphocytes., The Journal of experimental medicine, 1999-06-07 00:00:00. (Journal Article , Journal). Published, 06/07/1999.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=10359571
  • Schneider TJ, Fischer GM, Donohoe TJ, Colarusso TP, Rothstein TL, Schneider T., Fischer G., Donohoe T., Colarusso T., Rothstein T., A novel gene coding for a Fas apoptosis inhibitory molecule (FAIM) isolated from inducibly Fas-resistant B lymphocytes., The Journal of experimental medicine, 1999-03-15 00:00:00. (Journal Article , Journal). Published, 03/15/1999.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=10075978
  • Foote LC, Marshak-Rothstein A, Rothstein TL, Foote L., Marshak-Rothstein A., Rothstein T., Tolerant B lymphocytes acquire resistance to Fas-mediated apoptosis after treatment with interleukin 4 but not after treatment with specific antigen unless a surface immunoglobulin threshold is exceeded., The Journal of experimental medicine, 1998-03-16 00:00:00. (Journal Article , Journal). Published, 03/16/1998.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=9500787
  • Francis DA, Sen R, Rice N, Rothstein TL, Francis D., Sen R., Rice N., Rothstein T., Receptor-specific induction of NF-kappaB components in primary B cells., International immunology, 1998-03-01 00:00:00. (Journal Article , Journal). Published, 1998.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=9576616
  • Schneider TJ, Grillot D, Foote LC, Núñez GE, Rothstein TL, Schneider T., Grillot D., Foote L., Núñez G., Rothstein T., Bcl-x protects primary B cells against Fas-mediated apoptosis., Journal of immunology (Baltimore, Md. : 1950), 1997-11-15 00:00:00. (Journal Article , Journal). Published, 11/15/1997.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=9366408
  • Karras JG, Wang Z, Huo L, Frank DA, Rothstein TL, Karras J., Wang Z., Huo L., Frank D., Rothstein T., Induction of STAT protein signaling through the CD40 receptor in B lymphocytes: distinct STAT activation following surface Ig and CD40 receptor engagement., Journal of immunology (Baltimore, Md. : 1950), 1997-11-01 00:00:00. (Journal Article , Journal). Published, 11/01/1997.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=9379031
  • Wang Z, Karras JG, Colarusso TP, Foote LC, Rothstein TL, Wang Z., Karras J., Colarusso T., Foote L., Rothstein T., Unmethylated CpG motifs protect murine B lymphocytes against Fas-mediated apoptosis., Cellular immunology, 1997-09-15 00:00:00. (Journal Article , Journal). Published, 09/15/1997.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=9341746
  • Fine A, Anderson NL, Rothstein TL, Williams MC, Gochuico BR, Fine A., Anderson N., Rothstein T., Williams M., Gochuico B., Fas expression in pulmonary alveolar type II cells., The American journal of physiology, 1997-07-01 00:00:00. (Journal Article , Journal). Published, 07/1997.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=9252541
  • Karras JG, Wang Z, Huo L, Howard RG, Frank DA, Rothstein TL, Karras J., Wang Z., Huo L., Howard R., Frank D., Rothstein T., Signal transducer and activator of transcription-3 (STAT3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes., The Journal of experimental medicine, 1997-03-17 00:00:00. (Journal Article , Journal). Published, 03/17/1997.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=9091577
  • Jacobson BA, Foote LC, Panka DJ, Ju ST, Rothstein TL, Marshak-Rothstein A, Jacobson B., Foote L., Panka D., Ju S., Rothstein T., Marshak-Rothstein A., Unique site of autoantibody production in Fas-deficient mice., Annals of the New York Academy of Sciences, 1997-04-05 00:00:00. (Journal Article , Review , Book Series). Published, 1997.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=9186658
  • Foote LC, Marshak-Rothstein A, Rothstein TL, Foote L., Marshak-Rothstein A., Rothstein T., Inducible Fas-resistance mediated by IL-4 in activated B cells., Annals of the New York Academy of Sciences, 1997-04-05 00:00:00. (Journal Article , Book Series). Published, 1997.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=9186645
  • Francis DA, Sen R, Rothstein TL, Francis D., Sen R., Rothstein T., Receptor-specific regulation of NF-kappa B, c-Myc and Fas-mediated apoptosis in primary B cells., Current topics in microbiology and immunology, 1997-01-01 00:00:00. (Journal Article , Review , Book Series). Published, 1997.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=9308231
  • Jacobson BA, Rothstein TL, Marshak-Rothstein A, Jacobson B., Rothstein T., Marshak-Rothstein A., Unique site of IgG2a and rheumatoid factor production in MRL/lpr mice., Immunological reviews, 1997-04-01 00:00:00. (Journal Article , Review , Journal). Published, 1997.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=9176703
  • Huo L, Rothstein TL, Huo L., Rothstein T., Isolation and characterization of murine fra-1: induction mediated by CD40 and surface Ig is protein kinase C dependent., Journal of immunology (Baltimore, Md. : 1950), 1996-11-01 00:00:00. (Journal Article , Journal). Published, 11/01/1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8892610
  • Jacobson BA, Rothstein TL, Marshak-Rothstein A, Jacobson B., Rothstein T., Marshak-Rothstein A., The role of Fas/FasL interactions in the regulation of B cell function., Behring Institute Mitteilungen, 1996-10-01 00:00:00. (Journal Article , Review , Journal). Published, 10/1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8950476
  • Foote LC, Howard RG, Marshak-Rothstein A, Rothstein TL, Foote L., Howard R., Marshak-Rothstein A., Rothstein T., IL-4 induces Fas resistance in B cells., Journal of immunology (Baltimore, Md. : 1950), 1996-10-01 00:00:00. (Journal Article , Journal). Published, 10/01/1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8816375
  • Karras JG, Huo L, Wang Z, Frank DA, Zimmet JM, Rothstein TL, Karras J., Huo L., Wang Z., Frank D., Zimmet J., Rothstein T., Delayed tyrosine phosphorylation and nuclear expression of STAT1 following antigen receptor stimulation of B lymphocytes., Journal of immunology (Baltimore, Md. : 1950), 1996-09-15 00:00:00. (Journal Article , Journal). Published, 09/15/1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8805627
  • Wu M, Lee H, Bellas RE, Schauer SL, Arsura M, Katz D, FitzGerald MJ, Rothstein TL, Sherr DH, Sonenshein GE, Wu M., Lee H., Bellas R., Schauer S., Arsura M., Katz D., Fitzgerald M., Rothstein T., Sherr D., Sonenshein G., Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells., The EMBO journal, 1996-09-02 00:00:00. (Journal Article , Journal). Published, 09/02/1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8887559
  • Foote LC, Schneider TJ, Fischer GM, Wang JK, Rasmussen B, Campbell KA, Lynch DH, Ju ST, Marshak-Rothstein A, Rothstein TL, Foote L., Schneider T., Fischer G., Wang J., Rasmussen B., Campbell K., Lynch D., Ju S., Marshak-Rothstein A., Rothstein T., Intracellular signaling for inducible antigen receptor-mediated Fas resistance in B cells., Journal of immunology (Baltimore, Md. : 1950), 1996-09-01 00:00:00. (Journal Article , Journal). Published, 09/01/1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8757305
  • Fischer MB, Ma M, Goerg S, Zhou X, Xia J, Finco O, Han S, Kelsoe G, Howard RG, Rothstein TL, Kremmer E, Rosen FS, Carroll MC, Fischer M., Ma M., Goerg S., Zhou X., Xia J., Finco O., Han S., Kelsoe G., Howard R., Rothstein T., Kremmer E., Rosen F., Carroll M., Regulation of the B cell response to T-dependent antigens by classical pathway complement., Journal of immunology (Baltimore, Md. : 1950), 1996-07-15 00:00:00. (Journal Article , Journal). Published, 07/15/1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8752901
  • Karras JG, Wang Z, Coniglio SJ, Frank DA, Rothstein TL, Karras J., Wang Z., Coniglio S., Frank D., Rothstein T., Antigen-receptor engagement in B cells induces nuclear expression of STAT5 and STAT6 proteins that bind and transactivate an IFN-gamma activation site., Journal of immunology (Baltimore, Md. : 1950), 1996-07-01 00:00:00. (Journal Article , Journal). Published, 07/01/1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8683142
  • Schauer SL, Wang Z, Sonenshein GE, Rothstein TL, Schauer S., Wang Z., Sonenshein G., Rothstein T., Maintenance of nuclear factor-kappa B/Rel and c-myc expression during CD40 ligand rescue of WEHI 231 early B cells from receptor-mediated apoptosis through modulation of I kappa B proteins., Journal of immunology (Baltimore, Md. : 1950), 1996-07-01 00:00:00. (Journal Article , Journal). Published, 07/01/1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8683159
  • Rothstein TL, Rothstein T., Signals and susceptibility to programmed death in b cells., Current opinion in immunology, 1996-06-01 00:00:00. (Journal Article , Review , Journal). Published, 06/1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8793998
  • Xie H, Wang Z, Rothstein TL, Xie H., Wang Z., Rothstein T., Signaling pathways for antigen receptor-mediated induction of transcription factor CREB in B lymphocytes., Cellular immunology, 1996-05-01 00:00:00. (Journal Article , Journal). Published, 05/01/1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8620554
  • Ahearn JM, Fischer MB, Croix D, Goerg S, Ma M, Xia J, Zhou X, Howard RG, Rothstein TL, Carroll MC, Ahearn J., Fischer M., Croix D., Goerg S., Ma M., Xia J., Zhou X., Howard R., Rothstein T., Carroll M., Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen., Immunity, 1996-03-01 00:00:00. (Journal Article , Journal). Published, 03/1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8624815
  • Ozdemirli M, El-Khatib M, Foote LC, Wang JK, Marshak-Rothstein A, Rothstein TL, Ju ST, Ozdemirli M., El-Khatib M., Foote L., Wang J., Marshak-Rothstein A., Rothstein T., Ju S., Fas (CD95)/Fas ligand interactions regulate antigen-specific, major histocompatibility complex-restricted T/B cell proliferative responses., European journal of immunology, 1996-02-01 00:00:00. (Journal Article , Journal). Published, 02/1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8617312
  • Rothstein TL, Foote LC, Schneider TJ, Fischer GM, Jacobson BA, Lynch DH, Ju ST, Marshak-Rothstein A, Rothstein T., Foote L., Schneider T., Fischer G., Jacobson B., Lynch D., Ju S., Marshak-Rothstein A., Inducible resistance to Fas-mediated apoptosis in primary B lymphocytes., Advances in experimental medicine and biology, 1996-01-01 00:00:00. (Journal Article , Book Series). Published, 1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8910684
  • Schauer S., Wang Z., Wu M., Arsura M., Lee H., Sherr D., Rothstein T., Sonenshein G., Maintenance of NF-KB/rel and c-myc expression through modulation of 1kb proteins during CD40 ligand rescue of WEHI 231 B, FASEB Journal, 1996-01-01 00:00:00. (Journal). Published, 1996.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000128
  • Wang Z, Morris DL, Rothstein TL, Constitutive and inducible levels of egr-1 and c-myc early growth response gene expression in self-renewing B-1 lymphocytes., Cellular immunology, 1995-05-01 00:00:00. (Journal Article). Published, 05/1995.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=7743559
  • Wang Z., Morris D., Rothstein T., Constitutive and inducible levels of egr-1 and c-myc early growth response gene expression in self-renewing B-1 lymphocytes, Cellular Immunology, 1995-05-01 00:00:00. (Journal). Published, 05/1995.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000130
  • Rothstein TL, Wang JK, Panka DJ, Foote LC, Wang Z, Stanger B, Cui H, Ju ST, Marshak-Rothstein A, Rothstein T., Wang J., Panka D., Foote L., Wang Z., Stanger B., Cui H., Ju S., Marshak-Rothstein A., Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells., Nature, 1995-03-09 00:00:00. (Journal Article , Journal). Published, 03/09/1995.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=7533263
  • Francis DA, Karras JG, Ke XY, Sen R, Rothstein TL, Francis D., Karras J., Ke X., Sen R., Rothstein T., Induction of the transcription factors NF-kappa B, AP-1 and NF-AT during B cell stimulation through the CD40 receptor., International immunology, 1995-02-01 00:00:00. (Journal Article , Journal). Published, 02/1995.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=7537532
  • Dziennis S, Van Etten RA, Pahl HL, Morris DL, Rothstein TL, Blosch CM, Perlmutter RM, Tenen DG, Dziennis S., Van Etten R., Pahl H., Morris D., Rothstein T., Blosch C., Perlmutter R., Tenen D., The CD11b promoter directs high-level expression of reporter genes in macrophages in transgenic mice., Blood, 1995-01-15 00:00:00. (Journal Article , Journal). Published, 1995.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=7811988
  • Xie H, Rothstein TL, Xie H., Rothstein T., Protein kinase C mediates activation of nuclear cAMP response element-binding protein (CREB) in B lymphocytes stimulated through surface Ig., Journal of immunology (Baltimore, Md. : 1950), 1995-02-15 00:00:00. (Journal Article , Journal). Published, 1995.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=7836756
  • Huo L, Rothstein TL, Huo L., Rothstein T., Receptor-specific induction of individual AP-1 components in B lymphocytes., Journal of immunology (Baltimore, Md. : 1950), 1995-04-01 00:00:00. (Journal Article , Journal). Published, 1995.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=7534795
  • Wang Z, Karras JG, Howard RG, Rothstein TL, Wang Z., Karras J., Howard R., Rothstein T., Induction of bcl-x by CD40 engagement rescues sIg-induced apoptosis in murine B cells., Journal of immunology (Baltimore, Md. : 1950), 1995-10-15 00:00:00. (Journal Article , Journal). Published, 1995.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=7561075
  • Morris D., Rothstein T., Analysis of b-1 cell activation, Methods: A Companion to Methods in Enzymology, 1995-01-01 00:00:00. (Journal). Published, 01/01/1995.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000129
  • Tanguay DA, Dickinson JA, McManus BJ, Huo L, Rothstein TL, Chiles TC, Activation of AP-1 in primary B lymphocytes by surface immunoglobulin requires de novo Jun-B synthesis., Cellular immunology, 1994-10-15 00:00:00. (Journal Article). Published, 10/15/1994.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=7923384
  • Tanguay D., Tanguay J., McManus B., Huo L., Rothstein T., Chiles T., Activation of AP-1 in primary B lymphocytes by surface immunoglobulin requires de novo Jun-B synthesis, Cellular Immunology, 1994-10-01 00:00:00. (Journal). Published, 10/1994.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000131
  • Morris DL, Rothstein TL, Morris D., Rothstein T., Decreased surface IgM receptor-mediated activation of phospholipase C gamma 2 in B-1 lymphocytes., International immunology, 1994-07-01 00:00:00. (Journal Article , Journal). Published, 07/1994.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=7524640
  • Venkataraman L, Francis DA, Wang Z, Liu J, Rothstein TL, Sen R, Venkataraman L., Francis D., Wang Z., Liu J., Rothstein T., Sen R., Cyclosporin-A sensitive induction of NF-AT in murine B cells., Immunity, 1994-06-01 00:00:00. (Journal Article , Journal). Published, 06/1994.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=7889407
  • Huo L, Chung WH, Rothstein TL, Huo L., Chung W., Rothstein T., C-terminal sequence of the NF-kappa B p50 precursor from primary murine B-lymphocytes., Gene, 1994-02-25 00:00:00. (Journal Article , Journal). Published, 02/25/1994.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8112620
  • Lalmanach-Girard AC, Chiles TC, Parker DC, Rothstein TL, Lalmanach-Girard A., Chiles T., Parker D., Rothstein T., T cell-dependent induction of NF-kappa B in B cells., The Journal of experimental medicine, 1993-04-01 00:00:00. (Journal Article , Journal). Published, 04/01/1993.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8459216
  • Liu J, Sen R, Rothstein TL, Liu J., Sen R., Rothstein T., Abnormal kappa B-binding protein in the cytoplasm of a plasmacytoma cell line that lacks nuclear expression of NF-kappa B., Molecular immunology, 1993-04-01 00:00:00. (Journal Article , Journal). Published, 04/1993.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8464429
  • Morris DL, Rothstein TL, Morris D., Rothstein T., Abnormal transcription factor induction through the surface immunoglobulin M receptor of B-1 lymphocytes., The Journal of experimental medicine, 1993-03-01 00:00:00. (Journal Article , Journal). Published, 03/01/1993.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8436914
  • Xie H, Chiles TC, Rothstein TL, Xie H., Chiles T., Rothstein T., Induction of CREB activity via the surface Ig receptor of B cells., Journal of immunology (Baltimore, Md. : 1950), 1993-07-15 00:00:00. (Journal Article , Journal). Published, 1993.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=8393039
  • Wieselthier JS, Rothstein TL, Yu TL, Anderson T, Japowicz MC, Koh HK, Wieselthier J., Japowicz M., Rothstein T., Yu T., Anderson T., Koh H., Inefficacy of extracorporeal photochemotherapy in the treatment of B-cell chronic lymphocytic leukemia: preliminary results., American journal of hematology, 1992-10-01 00:00:00. (Clinical Trial , Journal Article , Journal). Published, 10/1992.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=1415173
  • Rothstein TL, Kolber DL, Cohen DP, ROTHSTEIN T., KOLBER D., COHEN D., CD5-like phorbol-ester responsiveness in conventional B cells activated through surface immunoglobulin., Annals of the New York Academy of Sciences, 1992-05-04 00:00:00. (Journal Article , Book Series). Published, 05/1992.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=1376037
  • Chiles TC, Rothstein TL, Chiles T., Rothstein T., Surface Ig receptor-induced nuclear AP-1-dependent gene expression in B lymphocytes., Journal of immunology (Baltimore, Md. : 1950), 1992-08-01 00:00:00. (Journal Article , Journal). Published, 1992.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=1634770
  • Liu JL, Chiles TC, Sen RJ, Rothstein TL, Liu J., Chiles T., Sen R., Rothstein T., Inducible nuclear expression of NF-kappa B in primary B cells stimulated through the surface Ig receptor., Journal of immunology (Baltimore, Md. : 1950), 1991-03-01 00:00:00. (Journal Article , Journal). Published, 03/01/1991.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=1993849
  • Kolber DL, Shultz LD, Rothstein TL, Phorbol ester responsiveness of murine Ly-1-lineage B cells from normal and viable motheaten mutant mice., European journal of immunology, 1991-03-01 00:00:00. (Journal Article). Published, 03/1991.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=2009913
  • Kolber D., Rothstein T., Shultz L., Phorbol ester responsiveness of murine Ly‐1‐lineage B cells from normal and viable motheaten mutant mice, European Journal of Immunology, 1991-03-01 00:00:00. (Journal). Published, 03/1991.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000132
  • Tilzey JF, Chiles TC, Rothstein TL, Tilzey J., Chiles T., Rothstein T., Jun-B gene expression mediated by the surface immunoglobulin receptor of primary B lymphocytes., Biochemical and biophysical research communications, 1991-02-28 00:00:00. (Journal Article , Journal). Published, 02/28/1991.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=1900155
  • Chiles TC, Liu JL, Rothstein TL, Chiles T., Liu J., Rothstein T., Cross-linking of surface Ig receptors on murine B lymphocytes stimulates the expression of nuclear tetradecanoyl phorbol acetate-response element-binding proteins., Journal of immunology (Baltimore, Md. : 1950), 1991-03-15 00:00:00. (Journal Article , Journal). Published, 1991.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=1900873
  • Cohen DP, Rothstein TL, Cohen D., Rothstein T., Elevated levels of protein kinase C activity and alpha-isoenzyme expression in murine peritoneal B cells., Journal of immunology (Baltimore, Md. : 1950), 1991-05-01 00:00:00. (Journal Article , Journal). Published, 1991.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=2016532
  • Rothstein TL, Kolber DL, Murphy TP, Cohen DP, Rothstein T., Kolber D., Murphy T., Cohen D., Induction of phorbol ester responsiveness in conventional B cells after activation via surface Ig., Journal of immunology (Baltimore, Md. : 1950), 1991-12-01 00:00:00. (Journal Article , Journal). Published, 1991.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=1719085
  • Murphy TP, Kolber DL, Rothstein TL, Murphy T., Kolber D., Rothstein T., Elevated expression of Pgp-1 (Ly-24) by murine peritoneal B lymphocytes., European journal of immunology, 1990-05-01 00:00:00. (Journal Article , Journal). Published, 05/1990.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=2192903
  • Miller PD, Pothoulakis C, Baeker TR, LaMont JT, Rothstein TL, Miller P., Pothoulakis C., Baeker T., LaMont J., Rothstein T., Macrophage-dependent stimulation of T cell-depleted spleen cells by Clostridium difficile toxin A and calcium ionophore., Cellular immunology, 1990-03-01 00:00:00. (Journal Article , Journal). Published, 03/1990.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=2105851
  • Rothstein TL, Rothstein T., Polyreactive low-affinity IgM antibodies produced by CD5+ B cells., Immunology today, 1990-05-01 00:00:00. (Comment , Letter , Journal). Published, 1990.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=1692464
  • Buckler AJ, Rothstein TL, Sonenshein GE, Buckler A., Rothstein T., Sonenshein G., Transcriptional control of c-myc gene expression during stimulation of murine B lymphocytes., Journal of immunology (Baltimore, Md. : 1950), 1990-07-15 00:00:00. (Journal Article , Journal). Published, 1990.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=2195118
  • Rothstein T., Polyreactive low-affinity IgM antibodies produced by CD5+B cells, Trends in Immunology, 1990-01-01 00:00:00. (Journal). Published, 1990.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000133
  • Wolfowicz CB, Lyons S, Mahon CA, Marshak-Rothstein A, Rothstein TL, Wolfowicz C., Lyons S., Mahon C., Marshak-Rothstein A., Rothstein T., Isolation of self-recognizing IgG2a monoclonal rheumatoid factors., Clinical immunology and immunopathology, 1989-08-01 00:00:00. (Journal Article , Journal). Published, 08/1989.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=2736811
  • van Haelst-Pisani C, Cragoe EJ Jr, Rothstein TL, van Haelst-Pisani C., Cragoe E., Rothstein T., Cytoplasmic alkalinization produced by the combination of anti-immunoglobulin antibody plus cytochalasin D in murine B lymphocytes., Experimental cell research, 1989-07-01 00:00:00. (Journal Article , Journal). Published, 07/1989.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=2786816
  • Cohen DP, Rothstein TL, Cohen D., Rothstein T., Adenosine 3',5'-cyclic monophosphate modulates the mitogenic responses of murine B lymphocytes., Cellular immunology, 1989-06-01 00:00:00. (Journal Article , Journal). Published, 06/1989.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=2470515
  • Rothstein TL, Rothstein T., Interleukin-4 enhances peritoneal B cell stimulation induced by phorbol ester., Cellular immunology, 1989-05-01 00:00:00. (Journal Article , Journal). Published, 05/1989.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=2785861
  • Wolfowicz CB, Sakorafas P, Rothstein TL, Marshak-Rothstein A, Wolfowicz C., Sakorafas P., Rothstein T., Marshak-Rothstein A., Oligoclonality of rheumatoid factors arising spontaneously in lpr/lpr mice., Clinical immunology and immunopathology, 1988-03-01 00:00:00. (Journal Article , Journal). Published, 03/1988.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3338196
  • Shlomchik MJ, Marshak-Rothstein A, Wolfowicz CB, Rothstein TL, Weigert MG, Shlomchik M., Marshak-Rothstein A., Wolfowicz C., Rothstein T., Weigert M., The role of clonal selection and somatic mutation in autoimmunity., Nature, 1987-08-27 00:00:00. (Journal Article , Journal). Published, 1988.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3498121
  • Buckler AJ, Kessler DJ, Duyao MP, Rothstein TL, Sonenshein GE, Buckler A., Kessler D., Duyao M., Rothstein T., Sonenshein G., Regulation of c-myc gene transcription in B lymphocytes: mechanisms of negative and positive control., Current topics in microbiology and immunology, 1988-01-01 00:00:00. (Journal Article , Journal). Published, 1988.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3265090
  • van Haelst C, Rothstein TL, Van Haelst C., Rothstein T., Cytochalasin stimulates phosphoinositide metabolism in murine B lymphocytes., Journal of immunology (Baltimore, Md. : 1950), 1988-02-15 00:00:00. (Journal Article , Journal). Published, 1988.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=2830337
  • Buckler AJ, Rothstein TL, Sonenshein GE, Buckler A., Rothstein T., Sonenshein G., Two-step stimulation of B lymphocytes to enter DNA synthesis: synergy between anti-immunoglobulin antibody and cytochalasin on expression of c-myc and a G1-specific gene., Molecular and cellular biology, 1988-03-01 00:00:00. (Journal Article , Journal). Published, 1988.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3285181
  • Rothstein TL, Kolber DL, Rothstein T., Kolber D., Peritoneal B cells respond to phorbol esters in the absence of co-mitogen., Journal of immunology (Baltimore, Md. : 1950), 1988-05-01 00:00:00. (Journal Article , Journal). Published, 1988.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=2966199
  • Rothstein TL, Kolber DL, Rothstein T., Kolber D., Anti-Ig antibody inhibits the phorbol ester-induced stimulation of peritoneal B cells., Journal of immunology (Baltimore, Md. : 1950), 1988-12-15 00:00:00. (Journal Article , Journal). Published, 1988.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3264301
  • ROTHSTEIN T., KOLBER D., Two Dual‐Signal Pathways for Stimulation of B Cells Mediated by Calcium Ionophores, Annals of the New York Academy of Sciences, 1987-05-01 00:00:00. (Book Series). Published, 05/1987.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000134
  • Baeker TR, Simons ER, Rothstein TL, Baeker T., Simons E., Rothstein T., Cytochalasin induces an increase in cytosolic free calcium in murine B lymphocytes., Journal of immunology (Baltimore, Md. : 1950), 1987-04-15 00:00:00. (Journal Article , Journal). Published, 1987.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3494083
  • Rothstein TL, Kolber DL, Simons ER, Baeker TR, Rothstein T., Kolber D., Simons E., Baeker T., Inhibition by phorbol esters of antiimmunoglobulin-induced calcium signalling and B-cell activation., Journal of cellular physiology, 1986-12-01 00:00:00. (Journal Article , Journal). Published, 12/1986.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3491085
  • Rothstein TL, Baeker TR, Miller RA, Kolber DL, Rothstein T., Baeker T., Miller R., Kolber D., Stimulation of murine B cells by the combination of calcium ionophore plus phorbol ester., Cellular immunology, 1986-10-15 00:00:00. (Journal Article , Journal). Published, 10/15/1986.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3492280
  • Baeker TR, Rothstein TL, Baeker T., Rothstein T., Effects of anti-IgM on mitogen-induced proliferation of human B-lymphocyte malignancies., Clinical immunology and immunopathology, 1986-05-01 00:00:00. (Journal Article , Journal). Published, 05/1986.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3084144
  • Rothstein TL, Rothstein T., Stimulation of B cells by sequential addition of anti-immunoglobulin antibody and cytochalasin., Journal of immunology (Baltimore, Md. : 1950), 1986-02-01 00:00:00. (Journal Article , Journal). Published, 1986.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3484500
  • Rothstein TL, Rothstein T., Stimulation of normal but not xid-defective B cells by calcium ionophore and cytochalasin., Journal of immunology (Baltimore, Md. : 1950), 1986-02-01 00:00:00. (Journal Article , Journal). Published, 1986.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3079798
  • Weissman D., Rothstein T., Marshak-Rothstein A., Growing xenogenic monoclonals in murine ascites, Federation Proceedings, 1985-01-01 00:00:00. (Journal). Published, 1985.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=900000135
  • Rothstein TL, Rothstein T., Anti-immunoglobulin in combination with cytochalasin stimulates proliferation of murine B lymphocytes., Journal of immunology (Baltimore, Md. : 1950), 1985-07-01 00:00:00. (Journal Article , Journal). Published, 1985.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3873486
  • Weissman D, Parker DJ, Rothstein TL, Marshak-Rothstein A, Weissman D., Parker D., Rothstein T., Marshak-Rothstein A., Methods for the production of xenogeneic monoclonal antibodies in murine ascites., Journal of immunology (Baltimore, Md. : 1950), 1985-08-01 00:00:00. (Journal Article , Journal). Published, 1985.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=4008923
  • Weissman D, Rothstein TL, Marshak-Rothstein A, Weissman D., Rothstein T., Marshak-Rothstein A., A rapid method for comparing monoclonal antibodies by limited proteolysis and electrophoresis., Hybridoma, 1985-12-01 00:00:00. (Journal Article , Journal). Published, 1985.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3905580
  • Baeker TR, Rothstein TL, Baeker T., Rothstein T., Proliferation of human malignant lymphocytes induced by anti-IgM independent of B cell growth factor., Journal of immunology (Baltimore, Md. : 1950), 1985-05-01 00:00:00. (Journal Article , Journal). Published, 1985.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=3872333
  • Rothstein TL, Miller RA, Parker DJ, Kelly E, Vastola AP, Marshak-Rothstein A, Rothstein T., Miller R., Parker D., Kelly E., Paul Vastola A., Marshak-Rothstein A., Induction of idiotope suppression in the anti-azophenylarsonate response of T-depleted A/J mice., The Journal of experimental medicine, 1984-04-01 00:00:00. (Journal Article , Journal). Published, 04/01/1984.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=6608575
  • Rothstein TL, Vastola AP, Rothstein T., Vastola A., Homologous monoclonal antibodies induce idiotope-specific suppression in neonates through maternal influence and in adults exposed during fetal and neonatal life., Journal of immunology (Baltimore, Md. : 1950), 1984-09-01 00:00:00. (Journal Article , Journal). Published, 1984.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=6747290
  • Margolies MN, Juszczak EC, Near R, Marshak-Rothstein A, Rothstein TL, Sato VL, Siekevitz M, Smith JA, Wysocki LJ, Gefter ML, MARGOLIES M., JUSZCZAK E., NEAR R., MARSHAK‐ROTHSTEIN A., ROTHSTEIN T., SATO V., SIEKEVITZ M., SMITH J., WYSOCKI L., GEFTER M., Structural correlates of idiotypy in the arsonate system., Annals of the New York Academy of Sciences, 1983-01-01 00:00:00. (Journal Article , Review , Book Series). Published, 12/1983.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=6424532
  • Rothstein TL, Gefter ML, Rothstein T., Gefter M., Affinity analysis of idiotype-positive and idiotype-negative Ars-binding hybridoma proteins and Ars-immune sera., Molecular immunology, 1983-02-01 00:00:00. (Journal Article , Journal). Published, 02/1983.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=6843553
  • Rothstein TL, Margolies MN, Gefter ML, Marshak-Rothstein A, Rothstein T., Margolies M., Gefter M., Marshak-Rothstein A., Fine specificity of idiotope suppression in the A/J anti-azophenylarsonate response., The Journal of experimental medicine, 1983-02-01 00:00:00. (Journal Article , Journal). Published, 02/01/1983.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=6185619
  • Mond JJ, Mage MG, Rothstein TL, Mosier DE, Herrod H, Asofsky R, Paul WE, Mond J., Mage M., Rothstein T., Mosier D., Herrod H., Asofsky R., Paul W., High anti-TNP plaque-forming cell potential of residual mIg+ cells in a T cell population., Journal of immunology (Baltimore, Md. : 1950), 1980-10-01 00:00:00. (Journal Article , Journal). Published, 1980.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=6774022
  • Rothstein TL, Mage M, Jones G, McHugh LL, Rothstein T., Mage M., Jones G., McHugh L., Cytotoxic T lymphocyte sequential killing of immobilized allogeneic tumor target cells measured by time-lapse microcinematography., Journal of immunology (Baltimore, Md. : 1950), 1978-11-01 00:00:00. (Journal Article , Journal). Published, 1978.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=309477
  • Rothstein TL, Mage MG, Mond J, McHugh LL, Rothstein T., Mage M., Mond J., McHugh L., Guinea pig antiserum to mouse cytotoxic T lymphocytes and their precursors., Journal of immunology (Baltimore, Md. : 1950), 1978-01-01 00:00:00. (Journal Article , Journal). Published, 1978.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=24072
  • Mage MG, McHugh LL, Rothstein TL, Mage M., McHugh L., Rothstein T., Mouse lymphocytes with and without surface immunoglobulin: preparative scale separation in polystyrene tissue culture dishes coated with specifically purified anti-immunoglobulin., Journal of immunological methods, 1977-01-01 00:00:00. (Journal Article , Journal). Published, 03/1977.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=15036
  • Mage MG, McHugh LL, Rothstein TL, Mage M., McHugh L., Rothstein T., Separation of graft-versus-host antigen-reactive cells in vitro., Transplantation proceedings, 1976-09-01 00:00:00. (Journal Article , Journal). Published, 1976.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=62430
  • Blum JJ, Rothstein TL, Blum J., Rothstein T., Lysosomes in Tetrahymena., Frontiers of biology, 1975-01-01 00:00:00. (Journal Article , Review , Journal). Published, 1975.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=820579
  • Rothstein TL, Blum JJ, Rothstein T., Blum J., Lysosomal physiology in Tetrahymena. 3. Pharmacological studies on acid hydrolase release and the ingestion and egestion of dimethylbenzanthracene particles., The Journal of cell biology, 1974-09-01 00:00:00. (Journal Article , Journal). Published, 09/01/1974.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=4152946
  • Rothstein TL, Blum JJ, Rothstein T., Blum J., Lysosomal physiology in Tetrahymena. IV. Effect of dichloroisoproterenol on the intracellular source of released acid hydrolases., Experimental cell research, 1974-07-01 00:00:00. (Journal Article , Journal). Published, 07/1974.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=4152223
  • Rothstein TL, Blum JJ, ROTHSTEIN T., BLUM J., Lysosomal physiology in Tetrahymena. II. Effect of culture age and temperature on the extracellular release of 3 acid hydrolases., The Journal of protozoology, 1974-02-01 00:00:00. (Journal Article , Journal). Published, 02/1974.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=4817979
  • Rothstein TL, Blum JJ, Rothstein T., Blum J., Lysosomal physiology in Tetrahymena. I. Effect of glucose, acetate, pyruvate, and carmine on intracellular content and extracellular release of three acid hydrolases., The Journal of cell biology, 1973-06-01 00:00:00. (Journal Article , Journal). Published, 06/01/1973.
    http://www.ncbi.nlm.nih.gov/pubmed/?term=4633442